Comparison of diagnostic accuracy of MRA and GPS algorithms using HR III device in glaucoma patients; [Glokom hastalari{dotless}nda hrt iii cihazi{dotless}nda mra ve gps algoritmalari{dotless}ni{dotless}n tani{dotless}sal deǧerlerinin karşi{dotless}laşti{dotless}ri{dotless}lmasi{dotless}]

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dc.contributor.authorOǧuz Ulusoy M.
dc.contributor.authorFatma Başer E.
dc.contributor.authorGöktuǧ Seymenoǧlu R.
dc.contributor.authorÖzcan Kayikçioǧlu R.
dc.date.accessioned2024-07-22T08:17:31Z
dc.date.available2024-07-22T08:17:31Z
dc.date.issued2014
dc.description.abstractObjectives: The aim of this study is to evaluate the diagnostic accuracy of Moorfields regression analysis (MRA) and glaucoma probability score (GPS) and to measure the agreement between these two programs in classifying eyes as normal or abnormal. Materials and Methods: The study included 150 glaucoma patients followed in our glaucoma unit and 120 control subjects without glaucoma. All subjects underwent total ophthalmological examination, standard achromatic perimetry, and imaging of the optic nerve head with the Heidelberg Retina Tomograph II (HRT), using HRT III software, Version 3.0. The HRT parameters were compared between the two groups. The diagnostic accuracies of the two classifications were measured when the borderline was taken as either normal (highest specificity criteria) or abnormal (highest sensitivity criteria). The agreement between them was calculated using the kappa (κ) coefficient. Results: All HRT parameters except height variation contour in our study showed statistically differences between the control and glaucoma groups (p=0.000). The parameters with the highest area under curves were GPS global score (0.817), vertical cup/disc ratio (0.816), cup/disc area (0.808), and cup area (0.783). According to the highest specificity criteria, MRA had a sensitivity of 66% and specificity of 89.1% and GPS had a sensitivity of 62.7% and specificity of 81.6%. According to the highest sensitivity criteria, MRA had a sensitivity of 85.3% and specificity of 68.3% and GPS had a sensitivity of 90% and specificity of 60.8%. A moderate agreement of 65.9% (178 eyes) with a κ coefficient of 0.47 was found between MRA and GPS. Conclusion: In conclusion, GPS and MRA had a similar sensitivity, but the specificity of MRA was found to be higher than that of GPS. A moderate agreement was found between these analysis programs.
dc.identifier.DOI-ID10.4274/tjo.55476
dc.identifier.issn13000659
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/17071
dc.language.isoEnglish
dc.publisherTurkish Ophthalmology Society
dc.rightsAll Open Access; Gold Open Access; Green Open Access
dc.subjectarea under the curve
dc.subjectarticle
dc.subjectcontrolled study
dc.subjectdiagnostic accuracy
dc.subjectdiagnostic test accuracy study
dc.subjectglaucoma
dc.subjectglaucoma probability score
dc.subjectHeidelberg retina tomography
dc.subjecthuman
dc.subjectimaging
dc.subjectmajor clinical study
dc.subjectMoorfields regression analysis
dc.subjectoptic nerve
dc.subjectperimetry
dc.subjectscoring system
dc.subjectsensitivity and specificity
dc.subjecttomography
dc.titleComparison of diagnostic accuracy of MRA and GPS algorithms using HR III device in glaucoma patients; [Glokom hastalari{dotless}nda hrt iii cihazi{dotless}nda mra ve gps algoritmalari{dotless}ni{dotless}n tani{dotless}sal deǧerlerinin karşi{dotless}laşti{dotless}ri{dotless}lmasi{dotless}]
dc.typeArticle

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