Effect of thermal energy produced by drilling on the facial nerve: Histopathologic evaluation in guinea pigs

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dc.contributor.authorAslan A.
dc.contributor.authorVatansever H.S.
dc.contributor.authorAslan G.G.
dc.contributor.authorEskiizmir G.
dc.contributor.authorGiray G.
dc.date.accessioned2024-07-22T08:23:49Z
dc.date.available2024-07-22T08:23:49Z
dc.date.issued2005
dc.description.abstractThe effect of thermal energy due to drilling around the facial nerve canal on the facial nerve was histopathologically evaluated in four guinea pigs. The bony canal of the facial nerve was drilled using a 3-mm diamond burr for one minute. The temperature changes on the facial nerve canal were noted before and after dissection. The temporal bones of the animals were histopathologically examined under light microscopy using haematoxylin & eosin (H&E) and solochrome cyanine staining for myelin, and immunohistochemical staining for neuronal nitric oxide synthase (nNOS). Compared to the control group, it was observed with H&E staining that there was oedema among the axonal fibres and with solochrome cyanine staining that the thickness of the myelin fibres was decreased, and that the severity and extent of nNOS activity was decreased in the axonal fibres. It was concluded that a temperature increase on the facial canal may potentially lead to inflammation of the nerve, and may also cause deterioration of nerve conduction to some extent.
dc.identifier.DOI-ID10.1258/0022215054516250
dc.identifier.issn00222151
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19701
dc.language.isoEnglish
dc.subjectAnimals
dc.subjectFacial Nerve
dc.subjectFacial Nerve Injuries
dc.subjectGuinea Pigs
dc.subjectHeat
dc.subjectHistocytochemistry
dc.subjectImmunohistochemistry
dc.subjectIntraoperative Complications
dc.subjectMastoid
dc.subjectModels, Animal
dc.subjectOsteotomy
dc.subjectcyanine dye
dc.subjecteosin
dc.subjecthematoxylin
dc.subjectmyelin
dc.subjectnitric oxide synthase
dc.subjectanimal model
dc.subjectanimal tissue
dc.subjectarticle
dc.subjectcontrolled study
dc.subjectdrill
dc.subjectedema
dc.subjectenergy
dc.subjectenzyme activity
dc.subjectfacial nerve
dc.subjectfacial nerve injury
dc.subjectguinea pig
dc.subjecthistochemistry
dc.subjecthistopathology
dc.subjectimmunohistochemistry
dc.subjectinflammation
dc.subjectmicroscopy
dc.subjectnerve conduction
dc.subjectnonhuman
dc.subjecttemperature
dc.subjecttemporal bone
dc.subjectthermal injury
dc.titleEffect of thermal energy produced by drilling on the facial nerve: Histopathologic evaluation in guinea pigs
dc.typeArticle

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