Manifestation of hashimoto's encephalopathy with psychotic signs: A case presentation

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dc.contributor.authorKisabay A.
dc.contributor.authorBalikci K.
dc.contributor.authorSari S.
dc.contributor.authorSelcuki D.
dc.date.accessioned2024-07-22T08:12:18Z
dc.date.available2024-07-22T08:12:18Z
dc.date.issued2016
dc.description.abstractHashimoto's encephalopathy (HE) is a rare autoimmune disease with unclear pathophysiology, developing on the basis of Hashimoto's thyroiditis (HT), associated with antithyroid antibodies, that presents with autoimmune, neuroendocrine, and neuropsychiatric findings. The disease is characterized by generalized or focal slowing in the EEG, elevated antithyroid antibody titration in the serum, elevated cerebrospinal fluid protein level, and the presence of antithyroid antibodies. HE is known as an autoimmune disorder of the central nervous system. With this feature, it is differentiated from cognitive alterations observed in hypothyroidism or hyperthyroidism. The response to treatment with corticosteroids in line with the autoimmune nature of HE supports this diagnosis. This report shows a case presenting with neuropsychiatric symptoms, elevated antithyroid antibody titration in the serum, and complete response to steroid therapy. A clear indicator for the diagnosis of HE has not yet been found. Therefore, other potential causes need to be considered in the differential diagnosis of this clinical picture until they can be excluded after investigations. With this case report, we want to emphasize that in differential diagnosis of patients presenting with a variety of neuropsychiatric symptoms, Hashimoto's encephalopathy-though being seen quite rarely-should not be disregarded, given the dramatic improvement of patients receiving a correct diagnosis and appropriate treatment.
dc.identifier.DOI-ID10.5350/DAJPN2016290110
dc.identifier.issn10188681
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/15976
dc.language.isoEnglish
dc.publisherYerkure Tanitim ve Yayincilik
dc.rightsAll Open Access; Hybrid Gold Open Access
dc.subjectC reactive protein
dc.subjectcyanocobalamin
dc.subjectlevothyroxine sodium
dc.subjectliothyronine
dc.subjectmethylprednisolone
dc.subjectprednisolone
dc.subjectquetiapine
dc.subjectthyroglobulin antibody
dc.subjectthyroid antibody
dc.subjectthyroid hormone
dc.subjectthyroid peroxidase antibody
dc.subjectthyrotropin
dc.subjectthyroxine
dc.subjecttumor marker
dc.subjectaged
dc.subjectagitation
dc.subjectArticle
dc.subjectattention deficit disorder
dc.subjectauditory hallucination
dc.subjectbehavior disorder
dc.subjectcase report
dc.subjectcognitive defect
dc.subjectcognitive function test
dc.subjectcyanocobalamin deficiency
dc.subjectdreaming
dc.subjectechography
dc.subjectelectroencephalography
dc.subjectfemale
dc.subjectHashimoto encephalopathy
dc.subjecthematology
dc.subjecthormone substitution
dc.subjecthospitalization
dc.subjecthuman
dc.subjecthypothyroidism
dc.subjectinsomnia
dc.subjectmagnetic resonance angiography
dc.subjectmedical examination
dc.subjectMini Mental State Examination
dc.subjectneurologic examination
dc.subjectnuclear magnetic resonance imaging
dc.subjectprotein blood level
dc.subjectpsychosis
dc.subjectsedimentation
dc.subjectthorax radiography
dc.subjectthyroid function test
dc.subjectthyroiditis
dc.subjectvasculitis
dc.subjectvery elderly
dc.subjectvisual hallucination
dc.subjectvitamin blood level
dc.titleManifestation of hashimoto's encephalopathy with psychotic signs: A case presentation
dc.typeArticle

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