An overview of biomolecules, immobilization methods and support materials of biosensors
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Date
2019
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Abstract
Purpose: Traditional analytical methods are often time-consuming and require bulky instruments, making their widespread implementation challenging. This paper aims to represent the principal concepts of biosensors as an introduction of this technology to readers and offers a comprehensive understanding of its functions. Design/methodology/approach: The authors provide descriptions of the components, characteristics and advantages of biosensors along with the immobilization methods, followed by a brief discussion. Findings: A biosensor is an analytical device comprising a specific biomolecule and a transducer in conjunction with an output system. The biomolecule recognizes a specific target which leads to a change in physicochemical properties of a system. This biorecognition phenomenon is later converted into a detectable signal by the transducer. Biosensors can essentially serve as rapid and cost-effective devices with excellent sensitivity and specificity for critical purposes in innumerable fields, ranging from scientific research to day-to-day applications. Originality/value: Here, the authors explain and discuss the approaches and challenges with the aim of leading to an interest in biosensor development and improving their applications. © 2018, Emerald Publishing Limited.
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Keywords
Analytic equipment , Biomolecules , Cost effectiveness , Physicochemical properties , Radioactive waste vitrification , Transducers , Analytical method , Bio recognition , Design/methodology/approach , Detectable signal , Immobilization method , Scientific researches , Sensitivity and specificity , Support materials , Biosensors