The relationship between placental elasticity and prenatal serum screening markers and Doppler indices

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dc.contributor.authorAkbaş M.
dc.contributor.authorKoyuncu F.M.
dc.contributor.authorErenel H.
dc.contributor.authorUlkumen B.A.
dc.contributor.authorMete T.O.
dc.date.accessioned2024-07-22T08:08:03Z
dc.date.available2024-07-22T08:08:03Z
dc.date.issued2020
dc.description.abstractIt has been shown that placental elasticity values were higher in pregnant women with preeclampsia and intrauterine growth restriction. The studies have been reported that prenatal serum screening markers and uterine artery Doppler parameters could be useful in the prediction of preeclampsia and intrauterine growth restriction. In this study, we aimed to investigate the relationship between placental elasticity values and these serum markers and Doppler indices in the first and second-trimester. 108 cases between 11-14 gestational weeks were enrolled for this study. Placental elasticity measurements were performed after the first-trimester combined test and Doppler assessment. The same procedures were repeated with the second-trimester triple test for 71 pregnant women who were followed-up. Correlation analysis of demographic characteristics, biochemical parameters and Doppler findings with placental elasticity values were performed. In the first-trimester, we found a statistically significant and positive correlation between placental elasticity values and bilateral uterine artery notching (r =0.193, p =0.045) and mean arterial pressure (r =0.398, p <0.001). Likewise, positive correlation was found between placental elasticity values and bilateral uterine artery notching (r =0.303, p =0.023) and mean arterial pressure (r =0.274, p =0.041) in the second-trimester. Our study showed that placental elasticity values were positively correlated with mean arterial pressure and bilateral uterine artery notching in the first and second-trimesters. In light of these findings, the utility of placental elasticity measurement in early gestation to predict pathologies due to insufficient placentation has to be proven with comprehensive studies. © 2020, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
dc.identifier.DOI-ID10.5505/ejm.2020.29981
dc.identifier.issn13010883
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/14239
dc.language.isoEnglish
dc.publisherYuzuncu Yil Universitesi Tip Fakultesi
dc.rightsAll Open Access; Gold Open Access
dc.subjectadult
dc.subjectarticle
dc.subjectcontrolled study
dc.subjectcorrelation analysis
dc.subjectdemography
dc.subjectelastography
dc.subjectfemale
dc.subjectfirst trimester pregnancy
dc.subjecthuman
dc.subjecthuman experiment
dc.subjecthuman tissue
dc.subjectmajor clinical study
dc.subjectmean arterial pressure
dc.subjectplacenta development
dc.subjectpregnant woman
dc.subjectprenatal screening
dc.subjectsecond trimester pregnancy
dc.subjectuterine artery
dc.titleThe relationship between placental elasticity and prenatal serum screening markers and Doppler indices
dc.typeArticle

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