Association between the ACE I/D gene polymorphism and physical performance in a homogeneous non-elite cohort

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dc.contributor.authorCam F.S.
dc.contributor.authorColakoglu M.
dc.contributor.authorSekuri C.
dc.contributor.authorColakoglu S.
dc.contributor.authorSahan Ç.
dc.contributor.authorBerdeli A.
dc.date.accessioned2024-07-22T08:24:02Z
dc.date.available2024-07-22T08:24:02Z
dc.date.issued2005
dc.description.abstractBackground: I/D polymorphism of the ACE gene may be associated with better endurance performance and a stronger response to exercise training. The aim of this study was to investigate the association between ACE gene polymorphism and athletic performance in a homogeneous cohort. Methods: Eighty-eight male non-elite Caucasian Turkish athletes with similar training backgrounds for at least for 6 months were studied for ACE gene polymorphisms by PCR analysis. Performance on the 60-meter sprint and middle-distance running tests were evaluated. Results: The distributions of the ACE I/D genotypes were 20.5%, 40.9%, and 38.6% for II, ID, and DD polymorphisms in the whole group (N = 88), respectively. The ACE DD genotype frequency was significantly higher in the superior group (56.7%) than in the poor (37.9%) and mediocre (20.7%) group in middle-distance running performance (χ2 = 11.778; p = 0.019). Conclusion: The ACE DD genotype may be related to better short-duration aerobic endurance performance. Larger homogeneous cohorts may help clarify the association between ACE I/D polymorphism and physical performance. © 2005 Canadian Society for Exercise Physiology.
dc.identifier.DOI-ID10.1139/h05-106
dc.identifier.issn10667814
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19775
dc.language.isoEnglish
dc.publisherHuman Kinetics Publishers Inc.
dc.subjectdipeptidyl carboxypeptidase
dc.subjectarticle
dc.subjectathlete
dc.subjectcohort analysis
dc.subjectcontrolled study
dc.subjectDNA polymorphism
dc.subjectendurance
dc.subjectexercise
dc.subjectfemale
dc.subjectgene frequency
dc.subjectgenotype
dc.subjecthuman
dc.subjectmale
dc.subjectphysical performance
dc.subjectpolymerase chain reaction
dc.subjectrunning
dc.subjecttraining
dc.titleAssociation between the ACE I/D gene polymorphism and physical performance in a homogeneous non-elite cohort
dc.typeArticle

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