Evaluation of subclinical multiple sclerosis patients using pattern visual evoked potentials and visual field test; [Subklinik multipl skleroz hastalari{dotless}ni{dotless}n desen görsel uyari{dotless}lmi{dotless}ş potansiyeller ve görme alani{dotless} testi ile deǧerlendirilmesi]
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Date
2014
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Abstract
Objectives: The aim of this study was to evaluate subclinical multiple sclerosis (MS) patients with normal visual acuity using pattern visual evoked potentials (PVEP) test and central 30-2 threshold visual feld (VF) test. Materials and Methods: A total of 60 patients, 30 of which had a definitive MS diagnosis and 30 who were healthy volunteers, were included in the study. The participants were divided into the following three groups: Group 1 - optic neuritis (+) MS patients, Group 2 - optic neuritis (-) MS patients, and Group 3 - control group. Using white on white perimetry, SITA FAST central 30-2 threshold VF tests and 1°-0.3° PVEP measurements were performed. MD, PSD, p100 latency (ms), p100 amplitude (μV), and central 0-10°, 0-20°, 0-30°, 10-20°, 10-30°, 20-30° retina sensitivities (db) were evaluated in all groups. Results: There was a significant difference in all parameters between Group 1 and Group 3 (p<0.05). There was a significant difference in p100 latency 1°- 0.3°, p100 amplitude 0.3°, central 0-30°, 10-30°, 20-30° between Group 2 and Group 3 (p<0.05). There was no significant difference in the parameters except for p100 amplitude 1° between Group 1 and Group 2 (p>0.05). Conclusion: The evaluation of PVEP and central 30° VF can be used to monitor disease prognosis in subclinical MS patients.