Evaluation of clinical course and neurocognition in children with self-limited infantile epilepsy in a turkish cohort study
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2015
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Abstract
The outcome of children with self-limited infantile epilepsy was reported to be normal psychosocial and cognitive development as a characteristic criterion. We aimed to investigate the clinical course and neurocognitive outcome in children with self-limited infantile epilepsy in a Turkish cohort. The clinical course, electroencephalographic (EEG) characteristics, neuroimaging, treatment, and outcome of children with self-limited infantile epilepsy were retrospectively analyzed. All infants were reevaluated with the Denver Developmental Screening Test in addition to neurologic examination. Of 44 patients, self-limited familial infantile epilepsy was diagnosed in 8 infants (18.2%) and self-limited nonfamilial infantile epilepsy in 28 (63.6%). Interictal EEGs and neurologic examinations were normal in all cases. Fine motor and gross motor skills, language, adaptive personal/social skills were near-normal in all patients with self-limited familial infantile epilepsy. Delay in language parameters was observed in 2 infants with self-limited nonfamilial infantile epilepsy. Language skills should be thoroughly evaluated with detailed neurocognitive screening tests in patients with self-limited infantile epilepsy. © The Author(s) 2014.
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Child, Preschool , Cognition Disorders , Cohort Studies , Electroencephalography , Epilepsy , Female , Humans , Infant , Male , Neurologic Examination , Neuropsychological Tests , Turkey , anticonvulsive agent , adaptive behavior , Article , cognition , cohort analysis , computer assisted tomography , Denver Developmental Screening Test , disease course , electroencephalography , epilepsy , epileptic state , evaluation study , febrile convulsion , female , focal epilepsy , follow up , gastroenteritis , human , infant , infant disease , language , male , motor performance , neuroimaging , neurologic examination , nuclear magnetic resonance imaging , onset age , outcome assessment , priority journal , retrospective study , self limited infantile epilepsy , social adaptation , tonic clonic seizure , Turkey (republic) , Turkish citizen , viral gastroenteritis , Cognition Disorders , complication , epidemiology , epilepsy , neuropsychological test , preschool child , Turkey