Intranasal steroids or radiofrequency turbinoplasty in persistent allergic rhinitis: Effects on quality of life and objective parameters

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dc.contributor.authorGunhan K.
dc.contributor.authorUnlu H.
dc.contributor.authorYuceturk A.V.
dc.contributor.authorSongu M.
dc.date.accessioned2024-07-22T08:20:06Z
dc.date.available2024-07-22T08:20:06Z
dc.date.issued2011
dc.description.abstractNasal congestion is a cardinal symptom of allergic rhinitis (AR). It is associated with decreased quality of life and difficult to treat as perceived by the patients. The purpose of this study is to evaluate the mid-term objective and subjective outcomes of management of nasal congestion using intranasal steroid (INS) therapy or radiofrequency turbinoplasty (RFT) in patients with persistent AR who have mucosal hypertrophy of the inferior turbinate. Fifty-five adult patients with AR, who claimed nasal congestion refractory to oral antihistamine (desloratadine) therapy, were randomized to INS (mometasone furoate) or temperature-controlled RFT treatment groups. Outcomes were determined by active anterior rhinomanometry, visual analog scale (VAS), and rhinoconjunctivitis quality of life questionnaire (RQLQ) at least 12 months after treatment. The median total nasal resistance decreased from 0.49 ± 0.17 to 0.39 ± 0.12 Pa/cm3/s (p = 0.42), and from 0.51 ± 0.18 to 0.29 ± 0.07 Pa/cm3/s (p = 0.003) with INS and RFT, respectively. RFT provided a better reduction in the perception of congestion in VAS scores. RQLQ scores improved significantly in both groups 1 year after treatment (mean follow-up 14.2 months) (p < 0.05). No adverse reactions were encountered in either group. Nasal congestion refractory to antihistamine appears to be improved by INS at some point, while reduced significantly by RFT in objective and subjective parameters. Both options are also effective in increasing the quality of life in patients with AR. RFT might be a safe and effective treatment of option in AR compared with INS. © 2010 Springer-Verlag.
dc.identifier.DOI-ID10.1007/s00405-010-1462-1
dc.identifier.issn14344726
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/17972
dc.language.isoEnglish
dc.subjectAdministration, Intranasal
dc.subjectAdult
dc.subjectCatheter Ablation
dc.subjectFemale
dc.subjectFollow-Up Studies
dc.subjectGlucocorticoids
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectProspective Studies
dc.subjectQuality of Life
dc.subjectQuestionnaires
dc.subjectRhinitis, Allergic, Seasonal
dc.subjectRhinomanometry
dc.subjectRhinoplasty
dc.subjectTreatment Outcome
dc.subjectYoung Adult
dc.subjectdesloratadine
dc.subjectmometasone furoate
dc.subjectoxymetazoline
dc.subjectadult
dc.subjectarticle
dc.subjectburn
dc.subjectcomparative study
dc.subjectcontrolled study
dc.subjectepistaxis
dc.subjectfemale
dc.subjecthuman
dc.subjecthypertrophy
dc.subjectinstillation site irritation
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectnose airway resistance
dc.subjectnose congestion
dc.subjectnose surgery
dc.subjectoutcome assessment
dc.subjectperennial rhinitis
dc.subjectpriority journal
dc.subjectquality of life
dc.subjectradiofrequency
dc.subjectradiofrequency turbinoplasty
dc.subjectrhinoconjunctivitis
dc.subjectrhinomanometry
dc.subjectsleep
dc.subjectsmelling disorder
dc.subjecttaste disorder
dc.subjectturbinate
dc.subjectvisual analog scale
dc.titleIntranasal steroids or radiofrequency turbinoplasty in persistent allergic rhinitis: Effects on quality of life and objective parameters
dc.typeArticle

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