Pathologic and clinical characteristics of elderly patients with breast cancer: A retrospective analysis of a multicenter study (anatolian society of medical oncology)

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dc.contributor.authorIal A.
dc.contributor.authorAkman T.
dc.contributor.authorYaman S.
dc.contributor.authorOzturk S.C.
dc.contributor.authorGeredeli C.
dc.contributor.authorBilici M.
dc.contributor.authorInanc M.
dc.contributor.authorHarputoglu H.
dc.contributor.authorDemirci U.
dc.contributor.authorBalakan O.
dc.contributor.authorCinkir H.Y.
dc.contributor.authorAlici S.
dc.contributor.authorColak D.
dc.contributor.authorSonmez O.U.
dc.contributor.authorGoksel G.
dc.contributor.authorDogu G.G.
dc.contributor.authorEngin H.
dc.contributor.authorUnal O.U.
dc.contributor.authorTamozlu T.
dc.contributor.authorBuyukberber S.
dc.contributor.authorBoruban C.M.
dc.contributor.authorIsikdogan A.
dc.date.accessioned2024-07-22T08:17:16Z
dc.date.available2024-07-22T08:17:16Z
dc.date.issued2014
dc.description.abstractThere is very little information about breast cancer characteristics, treatment choices, and survival among elderly patients. The purpose of this multicenter retrospective study was to examine the clinical, pathologic, and biologic characteristics of 620 breast cancer patients age 70 years or older. Between June 1991 and May 2012, 620 patients with breast cancer, recruited from 16 institutions, were enrolled in the retrospective study. Patients had smaller tumors at diagnosis; only 15% of patients had tumors larger than 5 cm. The number of patients who had no axillary lymph node involvement was 203 (32.7%). Ninety-three patients (15.0%) had metastatic disease at diagnosis. Patients were characterized by a higher fraction of pure lobular carcinomas (75.3%). The tumors of the elderly patients were also more frequently estrogen receptor (ER) positive (75.2%) and progesterone receptor (PR) positive (67.3%). The local and systemic therapies for breast cancer differed according to age. An association between age and overall survival has not been demonstrated in elderly patients with breast cancer. In conclusion, the biologic behavior of older patients with breast cancer differs from younger patients, and older patients receive different treatments.
dc.identifier.DOI-ID10.9738/INTSURG-D-13-00010
dc.identifier.issn00208868
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/17015
dc.language.isoEnglish
dc.publisherInternational College of Surgeons
dc.rightsAll Open Access; Bronze Open Access; Green Open Access
dc.subjectAdenocarcinoma
dc.subjectAge Factors
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectAxilla
dc.subjectBreast Neoplasms
dc.subjectBreast Neoplasms, Male
dc.subjectCombined Modality Therapy
dc.subjectFemale
dc.subjectHumans
dc.subjectLymphatic Metastasis
dc.subjectMale
dc.subjectNeoplasm Metastasis
dc.subjectPrognosis
dc.subjectRetrospective Studies
dc.subjectSurvival Analysis
dc.subjectadenocarcinoma
dc.subjectage
dc.subjectaged
dc.subjectaxilla
dc.subjectBreast Neoplasms
dc.subjectBreast Neoplasms, Male
dc.subjectclinical trial
dc.subjectfemale
dc.subjecthuman
dc.subjectlymph node metastasis
dc.subjectmale
dc.subjectmetastasis
dc.subjectmortality
dc.subjectmulticenter study
dc.subjectmultimodality cancer therapy
dc.subjectpathology
dc.subjectprognosis
dc.subjectretrospective study
dc.subjectsurvival analysis
dc.subjectvery elderly
dc.titlePathologic and clinical characteristics of elderly patients with breast cancer: A retrospective analysis of a multicenter study (anatolian society of medical oncology)
dc.typeArticle

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