Prognosis of hospitalized patients with community-acquired pneumonia

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dc.contributor.authorTokgoz Akyil F.
dc.contributor.authorYalcinsoy M.
dc.contributor.authorHazar A.
dc.contributor.authorCilli A.
dc.contributor.authorCelenk B.
dc.contributor.authorKilic O.
dc.contributor.authorSayiner A.
dc.contributor.authorKokturk N.
dc.contributor.authorSakar Coskun A.
dc.contributor.authorFiliz A.
dc.contributor.authorCakir Edis E.
dc.date.accessioned2024-07-22T08:09:55Z
dc.date.available2024-07-22T08:09:55Z
dc.date.issued2018
dc.description.abstractIntroduction: The long-term prognosis of patients with community-acquired pneumonia (CAP) has attracted increasing interest in recent years. The objective of the present study is to investigate the short and long-term outcomes in hospitalized patients with CAP and to identify the predictive factors associated with mortality. Patients and methods: The study was designed as a retrospective, multicenter, observational study. Hospitalized patients with CAP, as recorded in the pneumonia database of the Turkish Thoracic Society between 2011 and 2013, were included. Short-term mortality was defined as 30-day mortality and long-term mortality was assessed from those who survived 30 days. Predictive factors for short- and long-term mortality were analyzed. Results: The study included 785 patients, 68% of whom were male and the mean age was 67 ± 16 (18–92). The median duration of follow-up was 61.2 ± 11.8 (37–90) months. Thirty-day mortality was 9.2% and the median survival of patients surviving 30 days was 62.8 ± 4.4 months. Multivariate analysis revealed that advanced age, the absence of fever, a higher Charlson comorbidity score, higher blood urea nitrogen (BUN)/albumin ratios and lower alanine aminotransferase (ALT) levels were all predictors of long-term mortality. Conclusion: Long-term mortality following hospitalization for CAP is high. Charlson score and lack of fever are potential indicators for decreased long-term survival. As novel parameters, baseline BUN/albumin ratios and ALT levels are significantly associated with late mortality. Further interventions and closer monitoring are necessary for such subgroups of patients. © 2017 Sociedade Portuguesa de Pneumologia
dc.identifier.DOI-ID10.1016/j.rppnen.2017.07.010
dc.identifier.issn21735115
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/15000
dc.language.isoEnglish
dc.publisherElsevier Doyma
dc.rightsAll Open Access; Gold Open Access
dc.subjectC reactive protein
dc.subjectserum albumin
dc.subjectadult
dc.subjectaged
dc.subjectalanine aminotransferase blood level
dc.subjectarterial oxygen tension
dc.subjectArticle
dc.subjectCharlson Comorbidity Index
dc.subjectcohort analysis
dc.subjectcommunity acquired pneumonia
dc.subjectcomparative study
dc.subjectcontrolled study
dc.subjectcoughing
dc.subjectCURB 65
dc.subjectdemography
dc.subjectdyspnea
dc.subjectevaluation and follow up
dc.subjectfemale
dc.subjectfever
dc.subjectglucose blood level
dc.subjecthealth care survey
dc.subjecthematocrit
dc.subjecthospital admission
dc.subjecthospital patient
dc.subjecthuman
dc.subjectleukocyte count
dc.subjectlong term care
dc.subjectlung auscultation
dc.subjectlung diffusion
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmedical society
dc.subjectmiddle aged
dc.subjectmortality
dc.subjectmultivariate analysis
dc.subjectobservational study
dc.subjectoutcome assessment
dc.subjectpleura effusion
dc.subjectPneumonia Severity Index
dc.subjectpredictive value
dc.subjectpriority journal
dc.subjectprognosis
dc.subjectretrospective study
dc.subjectscoring system
dc.subjectshort course therapy
dc.subjectsurvival analysis
dc.subjectthorax disease
dc.subjectthorax pain
dc.subjectthorax surgery
dc.subjectunivariate analysis
dc.subjecturea nitrogen blood level
dc.titlePrognosis of hospitalized patients with community-acquired pneumonia
dc.typeArticle

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