How accurate is radiological imaging for perirenal fat and renal vein invasion in renal cell carcinoma?

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dc.contributor.authorUcer O.
dc.contributor.authorMuezzinoglu T.
dc.contributor.authorOzden E.
dc.contributor.authorAslan G.
dc.contributor.authorIzol V.
dc.contributor.authorBayazit Y.
dc.contributor.authorAltan M.
dc.contributor.authorAkdogan B.
dc.contributor.authorOzen H.
dc.contributor.authorSozen S.
dc.contributor.authorCetin S.
dc.contributor.authorSuer E.
dc.contributor.authorEsen B.
dc.contributor.authorBaltaci S.
dc.date.accessioned2024-07-22T08:05:36Z
dc.date.available2024-07-22T08:05:36Z
dc.date.issued2021
dc.description.abstractObjective: To evaluate the accuracy of radiological staging, especially renal venous and perirenal fat invasion, in renal cell carcinoma (RCC). Material and Methods: Data of 4823 renal tumour patients from Renal Tumor Database of Association of Uro-oncology in Turkey were evaluated. Of 4823 patients, 3309 RCC patients had complete radiological, and histopathological data were included to this study. The Pearson chi-squared test (χ2) was used to compare radiological and histopathological stages. Results: The mean (SD) age of 3309 patients was 58 (12.3). Preoperative radiological imaging was performed using computed tomography (CT) (n = 2510, 75.8%) or magnetic resonance imaging (MRI) (n = 799, 24.2%). There was a substantial concordance between radiological and pathological staging (к = 0.52, P <.001). Sensitivities of radiological staging in stages I, II, III and IV were 90.7%, 67.3%, 27.7% and 64.2%, respectively. The sensitivity in stage III was lower than the other stages. Subanalysis of stage IIIa cases revealed that, for perirenal fat invasion and renal vein invasion, sensitivity values were 15.4% and 11.3%, respectively. Conclusions: There was a substantial concordance between radiological (CT and/or MRI) and pathological T staging in RCC. However, this is not true for T3 cases. Sensitivity of preoperative radiological imaging in patients with pT3a tumours is insufficient and lower than the other stages. Consequently, preoperative imaging in patients with T3 RCC has to be improved, in order to better inform the patients regarding prognosis of their disease. © 2021 John Wiley & Sons Ltd
dc.identifier.DOI-ID10.1111/ijcp.14359
dc.identifier.issn13685031
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13184
dc.language.isoEnglish
dc.publisherJohn Wiley and Sons Inc
dc.rightsAll Open Access; Gold Open Access
dc.subjectCarcinoma, Renal Cell
dc.subjectHumans
dc.subjectKidney
dc.subjectKidney Neoplasms
dc.subjectNeoplasm Staging
dc.subjectRenal Veins
dc.subjectadult
dc.subjectaged
dc.subjectArticle
dc.subjectcancer patient
dc.subjectcancer prognosis
dc.subjectcancer staging
dc.subjectclinical evaluation
dc.subjectcomputer assisted tomography
dc.subjectdiagnostic accuracy
dc.subjectdiagnostic test accuracy study
dc.subjectfemale
dc.subjecthistopathology
dc.subjecthuman
dc.subjectkidney vein
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectnuclear magnetic resonance imaging
dc.subjectperirenal fat
dc.subjectpreoperative evaluation
dc.subjectrenal cell carcinoma
dc.subjectsensitivity analysis
dc.subjecttumor invasion
dc.subjectTurkey (republic)
dc.subjectcancer staging
dc.subjectdiagnostic imaging
dc.subjectkidney
dc.subjectkidney tumor
dc.subjectkidney vein
dc.subjectrenal cell carcinoma
dc.titleHow accurate is radiological imaging for perirenal fat and renal vein invasion in renal cell carcinoma?
dc.typeArticle

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