Community-acquired pneumonia in patients with chronic obstructive pulmonary disease requiring admission to the intensive care unit: Risk factors for mortality

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dc.contributor.authorCilli A.
dc.contributor.authorErdem H.
dc.contributor.authorKarakurt Z.
dc.contributor.authorTurkan H.
dc.contributor.authorYazicioglu-Mocin O.
dc.contributor.authorAdiguzel N.
dc.contributor.authorGungor G.
dc.contributor.authorBilge U.
dc.contributor.authorTasci C.
dc.contributor.authorYilmaz G.
dc.contributor.authorOncul O.
dc.contributor.authorDogan-Celik A.
dc.contributor.authorErdemli O.
dc.contributor.authorOztoprak N.
dc.contributor.authorSamur A.A.
dc.contributor.authorTomak Y.
dc.contributor.authorInan A.
dc.contributor.authorKaraboga B.
dc.contributor.authorTok D.
dc.contributor.authorTemur S.
dc.contributor.authorOksuz H.
dc.contributor.authorSenturk O.
dc.contributor.authorBuyukkocak U.
dc.contributor.authorYilmaz-Karadag F.
dc.contributor.authorOzcengiz D.
dc.contributor.authorKarakas A.
dc.contributor.authorSavasci U.
dc.contributor.authorOzgen-Alpaydin A.
dc.contributor.authorKilic E.
dc.contributor.authorElaldi N.
dc.contributor.authorBilgic H.
dc.date.accessioned2024-07-22T08:17:49Z
dc.date.available2024-07-22T08:17:49Z
dc.date.issued2013
dc.description.abstractPurpose: The aims of this study are to identify factors predicting mortality in patients with chronic obstructive pulmonary disease (COPD) and community-acquired pneumonia (CAP) requiring intensive care unit (ICU) admission and to examine whether noninvasive ventilation treatment reduces mortality. Materials and Methods: An analysis was performed on data from patients with CAP hospitalized in the ICUs of 19 different hospitals in Turkey between October 2008 and January 2011. Predictors of mortality were assessed by both univariate and multivariate statistical analyses. Results: Two hundred eleven patients with COPD and CAP were included. The overall ICU mortality was 23.9%. Noninvasive ventilation treatment (odds ratio [OR], 0.12; 95% confidence interval [CI], 0.03-0.49; P = .003), hypertension (OR, 0.13; 95% CI, 0.02-0.93; P = .042), bilateral infiltration (OR, 13.92; 95% CI, 2.94-65.84; P = .001), systemic corticosteroid treatment (OR, 0.19; 95% CI, 0.35-0.96; P = .045), length of ICU stay (OR, 0.65; 95% CI, 0.47-0.89; P = .007), and duration of invasive mechanical ventilation (OR, 1.11; 95% CI, 1.01-1.22; P = .032) were independent factors related to mortality. Conclusion: Noninvasive ventilation, hypertension, systemic corticosteroid treatment, and shorter ICU stay are associated with reduced mortality, whereas bilateral infiltration and longer duration of invasive mechanical ventilation are associated with increased risk of mortality in patients with COPD and CAP requiring ICU admission. © 2013 Elsevier Inc.
dc.identifier.DOI-ID10.1016/j.jcrc.2013.08.004
dc.identifier.issn15578615
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/17135
dc.language.isoEnglish
dc.subjectAdrenal Cortex Hormones
dc.subjectAged
dc.subjectCommunity-Acquired Infections
dc.subjectFemale
dc.subjectHealth Status Indicators
dc.subjectHospital Mortality
dc.subjectHumans
dc.subjectHypertension
dc.subjectIntensive Care Units
dc.subjectLength of Stay
dc.subjectMale
dc.subjectPneumonia
dc.subjectPredictive Value of Tests
dc.subjectPulmonary Disease, Chronic Obstructive
dc.subjectRespiration, Artificial
dc.subjectRisk Factors
dc.subjectSeverity of Illness Index
dc.subjectTurkey
dc.subjectCommunity-acquired pneumonia
dc.subjectCOPD
dc.subjectIntensive care unit
dc.subjectantibiotic agent
dc.subjecthypertensive factor
dc.subjectmethylprednisolone
dc.subjectAcinetobacter infection
dc.subjectadult
dc.subjectaged
dc.subjectarticle
dc.subjectchronic obstructive lung disease
dc.subjectcommunity acquired pneumonia
dc.subjectcontrolled study
dc.subjectdisease exacerbation
dc.subjectEnterobacteriaceae infection
dc.subjectEscherichia coli infection
dc.subjectfemale
dc.subjectGram negative infection
dc.subjecthospital admission
dc.subjecthospital patient
dc.subjecthuman
dc.subjecthypertension
dc.subjectintensive care unit
dc.subjectKlebsiella infection
dc.subjectlength of stay
dc.subjectlung infiltrate
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmortality
dc.subjectnonhuman
dc.subjectnoninvasive ventilation
dc.subjectParainfluenza virus infection
dc.subjectpneumococcal infection
dc.subjectprediction
dc.subjectPseudomonas infection
dc.subjectrisk assessment
dc.subjectrisk factor
dc.subjectrisk reduction
dc.subjectSerratia infection
dc.subjectStaphylococcus infection
dc.subjectsystemic therapy
dc.subjecttreatment duration
dc.subjectTurkey (republic)
dc.titleCommunity-acquired pneumonia in patients with chronic obstructive pulmonary disease requiring admission to the intensive care unit: Risk factors for mortality
dc.typeArticle

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