Levels of Melatonin in Continuous Spikes and Waves During Sleep

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dc.contributor.authorAyça S.
dc.contributor.authorAksoy H.U.
dc.contributor.authorTaştan İ.
dc.contributor.authorPolat M.
dc.date.accessioned2024-07-22T08:08:43Z
dc.date.available2024-07-22T08:08:43Z
dc.date.issued2019
dc.description.abstractLevels of melatonin have been reported before in children with epilepsy, but such has not been reported to date in those with continuous spikes and waves during sleep. The aim of the present study was to assess serum melatonin levels and melatonin circadian rhythm in patients with continuous spikes and waves during sleep and epilepsy. Serum melatonin was measured in 39 children stratified into 3 groups. Group 1 included 15 patients with continuous spikes and waves during sleep, group 2 included 12 epilepsy patients, and group 3 included 12 controls, respectively. Blood samples were taken from all participants at 1:00 am and 9:00 am and melatonin levels were measured using a quantitative enzyme-linked immunosorbent assay test. The 9:00 am melatonin levels of group 1 were significantly decreased and pair groups were compared. The P a value (representing a comparison between groups 1 and 2) was.002, the P b value (representing a comparison between groups 1 and 3) was.001, and the P c value (representing a comparison between groups 2 and 3) was.86. These findings suggest that the 9:00 am melatonin levels were significantly decreased in the comparison of groups 2 and 3. Further detailed research is necessary to determine the factors leading to the rapid decline of morning melatonin levels of children with continuous spikes and waves during sleep. © The Author(s) 2019.
dc.identifier.DOI-ID10.1177/0883073819828580
dc.identifier.issn08830738
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/14501
dc.language.isoEnglish
dc.publisherSAGE Publications Inc.
dc.subjectChild
dc.subjectCircadian Rhythm
dc.subjectElectroencephalography
dc.subjectEpilepsy
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMelatonin
dc.subjectSleep
dc.subjectmelatonin
dc.subjectmelatonin
dc.subjectaphasia
dc.subjectArticle
dc.subjectchild care
dc.subjectcircadian rhythm
dc.subjectclinical article
dc.subjectcontrolled study
dc.subjectelectroencephalography
dc.subjectenzyme linked immunosorbent assay
dc.subjectepilepsy
dc.subjecthuman
dc.subjectLennox Gastaut syndrome
dc.subjectpriority journal
dc.subjectsleep
dc.subjectsleep disorder
dc.subjectspike wave
dc.subjectblood
dc.subjectchild
dc.subjectepilepsy
dc.subjectfemale
dc.subjectmale
dc.subjectpathophysiology
dc.subjectphysiology
dc.subjectsleep
dc.titleLevels of Melatonin in Continuous Spikes and Waves During Sleep
dc.typeArticle

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