Enhancement of solid state fermentation for production of penicillin g on sugar beet pulp

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dc.contributor.authorTaşkin E.
dc.contributor.authorEltem R.
dc.contributor.authorSoyak E.
dc.date.accessioned2024-07-22T08:20:58Z
dc.date.available2024-07-22T08:20:58Z
dc.date.issued2010
dc.description.abstractIn this study, two local strains of Penicillium chrysogenum named EGEK458 and EGEK469 were selected for enhancement of Penicillin G (PenG) production under solid state fermentation (SSF) conditions. These two strains were selected among seven strains according to their fermentation yields for PenG production during previous tests under submerged fermentation conditions. Sugar beet pulp, an agro-industrial residue of the sugar industry, was used as an inert support for the first time in PenG production under SSF. In order to enhance the production of PenG, two points of moisture level and three concentration values of nutrients (impregnated in solid support), which are the key parameters in production of PenG, were compared. As the yields from solid and submerged fermentation were compared, 570U/g of PenG - almost 15 times higher quantities of its production vs. submerged conditions - were obtained under SSF conditions in 50 hours by the strain EGEK458. The conditions for the enhanced production of PenG were 65% moisture content with a four-fold concentrated nutrients impregnated solid support.
dc.identifier.issn19302126
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18389
dc.language.isoEnglish
dc.subjectBeta vulgaris subsp. vulgaris
dc.subjectPenicillium chrysogenum
dc.subjectDrug products
dc.subjectFermentation
dc.subjectMoisture
dc.subjectMoisture determination
dc.subjectNutrients
dc.subjectStrain
dc.subjectSugar (sucrose)
dc.subjectSugar beets
dc.subjectAgro-industrial residue
dc.subjectConcentration values
dc.subjectInert support
dc.subjectKey parameters
dc.subjectLocal strains
dc.subjectMoisture level
dc.subjectPenicillin G
dc.subjectPenicillium chrysogenum
dc.subjectSolid state fermentation
dc.subjectSolid supports
dc.subjectSubmerged condition
dc.subjectSubmerged fermentation
dc.subjectSugar beet pulp
dc.subjectTwo-point
dc.subjectSugar industry
dc.titleEnhancement of solid state fermentation for production of penicillin g on sugar beet pulp
dc.typeArticle

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