To evaluate the effects of antidepressant drugs on pregnancy outcomes in a university hospital of Turkey

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dc.contributor.authorCavusoglu T.
dc.contributor.authorAtak O.C.
dc.contributor.authorEser E.
dc.contributor.authorDariverenli E.
dc.contributor.authorAkca P.
dc.contributor.authorOlmez E.
dc.date.accessioned2024-07-22T08:06:36Z
dc.date.available2024-07-22T08:06:36Z
dc.date.issued2021
dc.description.abstractObjective: To assess the effects of antidepressant use on pregnancy outcomes. Methods: The cross-sectional study was conducted at the Department of Pharmacology, Manisa Celal Bayar University, Manisa, Turkey, and comprised pregnant women who were admitted to the Department of Gynaecology between 2008 and 2017 who had been prescribed antidepressant drugs before pregnancy and continued to use them during any week of their respective pregnancies. The women were contacted by telephone after delivery to obtain information about the pregnancy outcomes. Data was analysed using SPSS 23. Results: There were 183 women with a mean age of 31.3 ± 5.3 years (range: 18-44 years). There were congenital defects in the newborn in 11(7.65%) cases. The most commonly used antidepressant group was selective serotonin reuptake inhibitor 138(75.4%), and escitalopram was the most frequently used drug 46(25.1%). Spontaneous abortion rate was higher with escitalopram than the other antidepressants (p=0.062). Induced abortion rate was significantly higher in multidrug users compared to those on a single drug (p<0.05). Conclusion: Selective serotonin reuptake inhibitor was found to be the most used class of antidepressants during pregnancy due to the low side effects and teratogenic effects. When antidepressant treatment is necessary during pregnancy, a single drug can be more suitable. © 2021 Pakistan Medical Association. All rights reserved.
dc.identifier.DOI-ID10.47391/JPMA.805
dc.identifier.issn00309982
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13614
dc.language.isoEnglish
dc.publisherPakistan Medical Association
dc.rightsAll Open Access; Gold Open Access
dc.subjectAdult
dc.subjectAntidepressive Agents
dc.subjectCross-Sectional Studies
dc.subjectFemale
dc.subjectHospitals
dc.subjectHumans
dc.subjectInfant, Newborn
dc.subjectPregnancy
dc.subjectPregnancy Outcome
dc.subjectSerotonin Uptake Inhibitors
dc.subjectTurkey
dc.subjectagomelatine
dc.subjectantidepressant agent
dc.subjectcitalopram
dc.subjectclomipramine
dc.subjectduloxetine
dc.subjectescitalopram
dc.subjectfluoxetine
dc.subjectfluvoxamine
dc.subjectmilnacipran
dc.subjectmirtazapine
dc.subjectopipramol
dc.subjectparoxetine
dc.subjectserotonin
dc.subjectserotonin noradrenalin reuptake inhibitor
dc.subjectserotonin uptake inhibitor
dc.subjectsertraline
dc.subjecttetracyclic antidepressant agent
dc.subjecttrazodone
dc.subjecttricyclic antidepressant agent
dc.subjectvenlafaxine
dc.subjectvortioxetine
dc.subjectantidepressant agent
dc.subjectserotonin uptake inhibitor
dc.subjectabortion
dc.subjectadult
dc.subjectalcohol consumption
dc.subjectanxiety
dc.subjectanxiety disorder
dc.subjectArticle
dc.subjectattention deficit disorder
dc.subjectautism
dc.subjectcardiovascular malformation
dc.subjectcongenital hip dislocation
dc.subjectconsanguineous marriage
dc.subjectcontrolled study
dc.subjectcross-sectional study
dc.subjectdata analysis software
dc.subjectdepression
dc.subjectdrug exposure
dc.subjectdrug use
dc.subjectfemale
dc.subjecthuman
dc.subjectkidney agenesis
dc.subjectmajor clinical study
dc.subjectmiddle aged
dc.subjectmood disorder
dc.subjectnewborn
dc.subjectobsessive compulsive disorder
dc.subjectobstetric delivery
dc.subjectoutcome assessment
dc.subjectpatent ductus arteriosus
dc.subjectpregnancy
dc.subjectpregnancy outcome
dc.subjectpregnant woman
dc.subjectsmoking
dc.subjectsolitary kidney
dc.subjectspontaneous abortion
dc.subjectstrabismus
dc.subjecttelephone interview
dc.subjectteratogenesis
dc.subjectTurkey (republic)
dc.subjectuniversity hospital
dc.subjectepidemiology
dc.subjecthospital
dc.subjectturkey (bird)
dc.titleTo evaluate the effects of antidepressant drugs on pregnancy outcomes in a university hospital of Turkey
dc.typeArticle

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