The comparison of efficiency of bupivacaine-fentanyl with ropivacaine-fentanyl in patient controlled epidural analgesia for labour; [Hasta kontrollü epidural doǧum analjezisi için bupivakain fentanil ile ropivakain fentanilin etkinliǧinin karşilaştirilmasi]

Simple item page
dc.contributor.authorTopçu I.
dc.contributor.authorYentür E.A.
dc.contributor.authorTekin S.
dc.contributor.authorÇavuş Z.
dc.contributor.authorEkici N.Z.
dc.contributor.authorSakarya M.
dc.date.accessioned2024-07-22T08:24:18Z
dc.date.available2024-07-22T08:24:18Z
dc.date.issued2004
dc.description.abstractIn this prospective, randomized, double-blinded study we aimed to evaluate the efficiency of 1μg mL-1 fentanyl with 0.125% bupivacaine and 1μg mL-1 fentanyl with 0.125% ropivacaine by patient controlled epidural analgesia (PCEA) for labour. The study was performed in 2 groups; each consisted of 20 pregnants which had healthy, single fetus in 36-41 gestational weeks with normal fetal pulse pattern in vertex position, 3-6 cm of cervical dilatation and at active phase of labour. Solution of 1μg mL-1 fentanyl with 0.125% ropivacaine was applied to Group I and 1μg mL-1 fentanyl with 0.125% bupivacaine to Group II. PCEA was programmed as 5 ml bolus dose, 10 minutes lock-out (without basal infusion, and 1-4 h limit) and 10 mL loading dose. Patients' pain was evaluated by VAS (visual analog scale) (0-100mm), sensory block by PinPrick test (0-3) and motor block by modified Bromage scale. Maternal mean arterial pressure (MAP), heart rate (HR) and fetal HR were recorded during the labour. Umblical artery blood pH, APGAR of fetus and patient satisfaction after delivery (1-5) were assessed. Mode of delivery (normal, operative and cesarean), side-effects, duration of labour and analgesics consumption for the first and second stages of labour were recorded by calculating the values via PCEA. No differences were obtained in the evaluation of MAP, HR, fetal HR, VAS, sensory block, amount of analgesics solution, mode of delivery, duration of labour, side effects and patient satisfaction between the groups. However, lesser motor block was observed in ropivacaine/fentanyl group rather than bupivacaine/fentanyl group (p<0.05). Consequently, both 1μg mL-1 fentanyl with 0.125% ropivacaine and 1μg mL-1 fentanyl with 0.125% bupivacaine by patient controlled epidural analgesia (PCEA) for labour, provided sufficient and trustworthy analgesia. Similar effects were obtained on hemodynamics but because of lesser motor block effect, we propose that ropivacaine more superior for labour analgesia.
dc.identifier.issn13000578
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19913
dc.language.isoTurkish
dc.subjectbupivacaine
dc.subjectfentanyl
dc.subjectropivacaine
dc.subjectadult
dc.subjectApgar score
dc.subjectarterial pH
dc.subjectarticle
dc.subjectbolus injection
dc.subjectcesarean section
dc.subjectclinical article
dc.subjectclinical trial
dc.subjectcontrolled clinical trial
dc.subjectcontrolled study
dc.subjectdouble blind procedure
dc.subjectdrug efficacy
dc.subjectepidural anesthesia
dc.subjectfemale
dc.subjectfetus heart rate
dc.subjectgestational age
dc.subjectheart rate
dc.subjecthemodynamics
dc.subjecthuman
dc.subjectlabor
dc.subjectlabor pain
dc.subjectmean arterial pressure
dc.subjectmotor nerve block
dc.subjectobstetric anesthesia
dc.subjectpain assessment
dc.subjectpatient controlled analgesia
dc.subjectpatient satisfaction
dc.subjectpregnancy
dc.subjectprick test
dc.subjectprospective study
dc.subjectrandomized controlled trial
dc.subjectside effect
dc.subjectumbilical artery
dc.subjectvaginal delivery
dc.subjectvisual analog scale
dc.titleThe comparison of efficiency of bupivacaine-fentanyl with ropivacaine-fentanyl in patient controlled epidural analgesia for labour; [Hasta kontrollü epidural doǧum analjezisi için bupivakain fentanil ile ropivakain fentanilin etkinliǧinin karşilaştirilmasi]
dc.typeArticle

Files

Collections

Scopus Koleksiyonu