Maternal serum perlecan levels in women with preeclampsia

dc.contributor.authorAkbas, M
dc.contributor.authorKoyuncu, FM
dc.contributor.authorArtunc-Ulkumen, B
dc.contributor.authorTaneli, F
dc.contributor.authorOzdemir, H
dc.date.accessioned2025-04-10T10:26:47Z
dc.date.available2025-04-10T10:26:47Z
dc.description.abstractObjective: Perlecan is an extracellular matrix proteoglycan suggested to maintain endothelial functions. We aimed to measure maternal serum perlecan levels in different preeclampsia phenotypes. Methods: This study included 50 women with preeclampsia and 30 healthy pregnant women. Results: Serum perlecan levels were significantly higher (p = 0.016) in preeclamptic women with severe features(n = 23) than preeclampsia patients(n = 27). There were no statistically significant differences in serum perlecan levels between the early-onset preeclampsia(n = 25), late-onset preeclampsia(n = 25), and healthy pregnancies. Conclusion: Our findings suggest that preeclamptic women with severe features have higher serum perlecan levels than women with preeclampsia.
dc.identifier.e-issn1525-6065
dc.identifier.issn1064-1955
dc.identifier.urihttp://hdl.handle.net/20.500.14701/34406
dc.language.isoEnglish
dc.titleMaternal serum perlecan levels in women with preeclampsia
dc.typeArticle

Files