Efficacy of topical brinzolamide treatment in posterior microphthalmos-related macular cystoid lesions: A case series
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2020
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Abstract
The aim of this study was to report the outcome of topical brinzolamide 1% treatment on macular cystoid lesions resembling retinoschisis in 4 patients diagnosed with posterior microphthalmia. The medical records of 4 patients with a clinical diagnosis of posterior microphthalmia who had started topical brinzolamide 1% treatment were reviewed. Visual acuity, central foveal thickness, and cystoid lesion area percentage were used to evaluate treatment response. In the follow-up, there was a decrease in central foveal thicknesses and cystoid lesion area percentages in both eyes of 3 of the patients. However, 1 patient showed increases in both parameters. Visual acuity remained stable in 5 eyes and increased in 3 eyes. Topical brinzolamide treatment may have some positive effects on macular cystoid lesions in selected cases. © 2020 by Turkish Ophthalmological Association Turkish Journal of Ophthalmology, published by Galenos Publishing House.
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Administration, Topical , Adolescent , Adult , Carbonic Anhydrase Inhibitors , Child , Child, Preschool , Female , Humans , Macular Edema , Male , Microphthalmos , Sulfonamides , Thiazines , Tomography, Optical Coherence , Visual Acuity , brinzolamide , brinzolamide , carbonate dehydratase inhibitor , sulfonamide , thiazine derivative , adolescent , adult , anterior eye chamber depth , Article , B scan , case report , central foveal thickness , central retinal thickness , child , clinical article , drug efficacy , eye axis length , female , fluorescence angiography , follow up , fundus flourescein angiography , human , intraocular pressure , male , microphthalmia , retina examination , retina macula cystoid edema , retrospective study , spectral domain optical coherence tomography , treatment response , visual acuity , complication , macular edema , microphthalmia , optical coherence tomography , preschool child , procedures , topical drug administration , visual acuity