Evaluation of intraocular pressure and cataract formation following the long-term use of nasal corticosteroids

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dc.contributor.authorÖztürk F.
dc.contributor.authorYücetürk A.V.
dc.contributor.authorKurt E.
dc.contributor.authorÜnlü H.H.
dc.contributor.authorIlker S.S.
dc.date.accessioned2024-07-22T08:25:47Z
dc.date.available2024-07-22T08:25:47Z
dc.date.issued1998
dc.description.abstractIt is possible that corticosteroids administered via nasal spray might reach ocular structures in levels sufficient to provoke an ocular hypertensive response and cause posterior subcapsular cataracts (PSCs) in susceptible individuals. In the present study, 26 patients who had undergone endoscopic sinus surgery were evaluated prospectively with respect to intraocular pressure and PSC formation following the use of nasal steroids for at least three months. Eighteen patients (69%) self-administered 200 μg/day of budesonide nasal spray twice daily, and eight patients (31%) self- administered 200 μg/day of beclomethasone dipropionate nasal spray twice daily, for a period of three to 19 months (mean 8.8 ± 3.6 months). Ophthalmologic examination, tonometry, visual field testing and biomicroscopic studies revealed no evidence of ocular hypertension or PSCs during postoperative follow-up. We conclude that intranasal corticosteroids can be used safely for prolonged periods without increasing the risk of ocular hypertension or PSCs.
dc.identifier.DOI-ID10.1177/014556139807701012
dc.identifier.issn01455613
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20578
dc.language.isoEnglish
dc.publisherMedquest Communications LLC
dc.subjectbudesonide
dc.subjectcorticosteroid
dc.subjectnose spray
dc.subjectadult
dc.subjectaged
dc.subjectarticle
dc.subjectbiomicroscopy
dc.subjectcataract
dc.subjectclinical article
dc.subjectclinical feature
dc.subjectcontrolled study
dc.subjectcorticosteroid therapy
dc.subjectdrug absorption
dc.subjectdrug disposition
dc.subjectfemale
dc.subjectglaucoma
dc.subjecthuman
dc.subjectintranasal drug administration
dc.subjectintraocular pressure
dc.subjectlong term care
dc.subjectmale
dc.subjectparanasal sinus disease
dc.subjecttonometry
dc.subjectvisual field
dc.titleEvaluation of intraocular pressure and cataract formation following the long-term use of nasal corticosteroids
dc.typeArticle

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