Serological prevalence of Helicobacter pylori in children with recurrent abdominal pain in Manisa region, Western Turkey

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dc.contributor.authorKasirga E.
dc.contributor.authorErtan P.
dc.contributor.authorTosun S.
dc.contributor.authorSanlidag T.
dc.contributor.authorTansug N.
dc.contributor.authorOnag A.
dc.date.accessioned2024-07-22T08:25:19Z
dc.date.available2024-07-22T08:25:19Z
dc.date.issued2002
dc.description.abstractObjective: The purpose of this study was to evaluate the serological prevalence of Helicobacter pylori infection in asymptomatic and symptomatic (recurrent abdominal pain) children in Manisa region, Western Turkey. Design: To study the rate of infection by Helicobacter pylori in children, the prevalence of IgG antibodies to Helicobacter pylori was determined. Materials and Methods: Fifty-five symptomatic (25 boys and 30 girls) and one hundred sixty-four asymptomatic (82 boys and 82 girls) children between 3-15 years of age were tested for anti-Helicobacter pylori IgG. Serum samples collected were tested for IgG antibodies against Helicobacter pylori by enzyme-linked immunosorbent assay (ELISA) using commercial kits. Mean titers >20 U/ml were considered positive for specific IgG antibody. Results: The prevalence of anti-H. pylori IgG antibody was 65.5% in symptomatic and 35.4% in asymptomatic children. The seroprevalence was increased significantly with age in children with recurrent abdominal pain (chi-square= 18.09; p< 0.001). There was a significant difference in the appearance rate of IgG antibodies between asymptomatic and symptomatic children (chi-square= 15.22; p< 0.001). Conclusion: This study shows that Helicobacter pylori seropositivity is more common in children with recurrent abdominal pain than in asymptomatic children living in Manisa region, Western Turkey.
dc.identifier.issn13412051
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20369
dc.language.isoEnglish
dc.subjectimmunoglobulin G antibody
dc.subjectabdominal pain
dc.subjectadolescent
dc.subjectantibody blood level
dc.subjectarticle
dc.subjectclinical article
dc.subjectenzyme linked immunosorbent assay
dc.subjectfemale
dc.subjectHelicobacter infection
dc.subjectHelicobacter pylori
dc.subjecthuman
dc.subjecthuman tissue
dc.subjectimmunoglobulin blood level
dc.subjectinfection rate
dc.subjectmale
dc.subjectrecurrent disease
dc.subjectschool child
dc.subjectseroprevalence
dc.subjectsymptom
dc.subjectTurkey (republic)
dc.titleSerological prevalence of Helicobacter pylori in children with recurrent abdominal pain in Manisa region, Western Turkey
dc.typeArticle

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