Phenolic profile, enzyme inhibitory and antioxidant activities of two endemic Nepeta species: Nepeta nuda subsp. glandulifera and N. cadmea

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dc.contributor.authorSarikurkcu C.
dc.contributor.authorEskici M.
dc.contributor.authorKaranfil A.
dc.contributor.authorTepe B.
dc.date.accessioned2024-07-22T08:09:11Z
dc.date.available2024-07-22T08:09:11Z
dc.date.issued2019
dc.description.abstractIt is known that the local people commonly use some Nepeta species as diuretic, spasmolytic, bronchodilator and sedative agents. In addition, these species are also used topically due to their antiseptic properties. This study aimed to deal with the in vitro antioxidant and enzyme inhibitory activities of the methanolic extracts of two endemic. Nepeta species (Nepeta nuda L. subsp. glandulifera Hub.-Mor. & Davis and N. cadmea Boiss.) from Turkey. N. nuda subsp. glandulifera was found to contain more phenolics and flavonoids than N. cadmea. N. nuda subsp. glandulifera was also found to have considerable amounts of chlorogenic and ferulic acids (63.52 and 14.65 mg/g extract), and showed higher antioxidant activity in almost all test systems, except metal chelating assay. Meanwhile in β-carotene bleaching assay, it was found to be as active as BHT and trolox (91.23%). In the enzyme inhibition assay, the extracts showed weak inhibitory activity on AChE, α-amylase and α-glucosidase. Inhibitory activity of N. nuda subsp. glandulifera on these enzymes was found to be 1.26 mg GALAEs (galanthamine equivalents)/g extract, 0.36 and 3.67 mmol ACEs (acarbose equivalents)/g extract, respectively. © 2018 South African Association of Botanists
dc.identifier.DOI-ID10.1016/j.sajb.2018.09.008
dc.identifier.issn02546299
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/14708
dc.language.isoEnglish
dc.publisherElsevier B.V.
dc.rightsAll Open Access; Hybrid Gold Open Access
dc.subjectTurkey
dc.subjectNepeta
dc.subjectNepeta cadmea
dc.subjectNepeta nuda
dc.subjectangiosperm
dc.subjectantioxidant
dc.subjectbleaching
dc.subjectendemic species
dc.subjectenzyme activity
dc.subjectinhibition
dc.subjectliquid chromatography
dc.subjectphenolic compound
dc.subjectplant extract
dc.subjectsubspecies
dc.titlePhenolic profile, enzyme inhibitory and antioxidant activities of two endemic Nepeta species: Nepeta nuda subsp. glandulifera and N. cadmea
dc.typeArticle

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