Computational fluid dynamics simulation in scaling-up of airlift photobioreactor for astaxanthin production

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dc.contributor.authorAslanbay Guler B.
dc.contributor.authorDeniz I.
dc.contributor.authorDemirel Z.
dc.contributor.authorImamoglu E.
dc.date.accessioned2024-07-22T08:08:14Z
dc.date.available2024-07-22T08:08:14Z
dc.date.issued2020
dc.description.abstractThe unicellular green microalga Haematococcus pluvialis accumulates large amounts of the red ketocarotenoid astaxanthin. Aiming to cultivate these microalgae with high astaxanthin efficiency, cultivations were scaled-up from 1000 mL bottle to 2 L and 8 L airlift photobioreactor using volumetric power consumption rate (W/m3) as scale up strategy. After cultivations, computational fluid dynamics (CFD) simulation was used to investigate the flow patterns, mixing efficiency and gas holdup profile within the 2 L photobioreactor. At the end, astaxanthin content was enhanced with increasing the cultivation volume and highest astaxanthin amount of 49.39 ± 1.64 mg/g cell was obtained in 8 L photobioreactor. Hydrodynamic characteristics of photobioreactor was simulated and gas holdup showed difference between the riser and the downcomer regions. Velocity profiles of air and medium had higher values inside the draft tube than obtained in downcomer region. However liquid circulation was achieved from draft tube to the downcomer, mixing was not provided effectively considering the turbulence kinetic energy. For the further research, some developments about column configuration, sparger diameter may be necessary to enhance the mixing characteristics. © 2019 The Society for Biotechnology, Japan
dc.identifier.DOI-ID10.1016/j.jbiosc.2019.06.010
dc.identifier.issn13891723
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/14306
dc.language.isoEnglish
dc.publisherElsevier B.V.
dc.subjectChlorophyta
dc.subjectHydrodynamics
dc.subjectKinetics
dc.subjectLight
dc.subjectMicroalgae
dc.subjectPhotobioreactors
dc.subjectXanthophylls
dc.subjectAir
dc.subjectAlgae
dc.subjectBottles
dc.subjectEnergy efficiency
dc.subjectKinetic energy
dc.subjectKinetics
dc.subjectMixing
dc.subjectPhotobioreactors
dc.subjectastaxanthin
dc.subjectastaxanthin
dc.subjectxanthophyll
dc.subjectAstaxanthin
dc.subjectComputational fluid dynamics simulations
dc.subjectHaematococcus pluvialis
dc.subjectHydrodynamic characteristics
dc.subjectScale-up
dc.subjectSimulation
dc.subjectTurbulence kinetic energy
dc.subjectVolumetric power consumption
dc.subjectalgal cell culture
dc.subjectArticle
dc.subjectcomputational fluid dynamics
dc.subjectcomputer simulation
dc.subjectcontrolled study
dc.subjectenergy consumption
dc.subjectflow rate
dc.subjectgas
dc.subjectHaematococcus pluvialis
dc.subjecthydrodynamics
dc.subjectliquid
dc.subjectnonhuman
dc.subjectprocess development
dc.subjectscale up
dc.subjectvelocity
dc.subjectvitamin metabolism
dc.subjectvolumetry
dc.subjectchemistry
dc.subjectgreen alga
dc.subjectgrowth, development and aging
dc.subjectkinetics
dc.subjectlight
dc.subjectmetabolism
dc.subjectmicroalga
dc.subjectphotobioreactor
dc.subjectradiation response
dc.subjectComputational fluid dynamics
dc.titleComputational fluid dynamics simulation in scaling-up of airlift photobioreactor for astaxanthin production
dc.typeArticle

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