An experience with plasma exhcange treatment of acute lymphoblastic leukemia in a case with fulminant hepatitis related to l-asparaginase

dc.contributor.authorBilgir O.
dc.contributor.authorCalan M.
dc.contributor.authorBilgir F.
dc.contributor.authorCagliyan G.
dc.contributor.authorArslan O.
dc.date.accessioned2024-07-22T08:18:17Z
dc.date.available2024-07-22T08:18:17Z
dc.date.issued2013
dc.description.abstractAcute lymphoblastic leukemia (ALL) is a malignant disorder resulting from the clonal proliferation of lymphoid precursors with arrested maturation. l-asparaginase is commonly used in combination chemotherapy of both pediatric and adult acute lymphoblastic leukemias. The most commonly encountered side effects of l-asparaginase are hypersensitivity reactions like pyrexia, urticaria, skin rash, and respiratory distress. There are also other side effects like anaphylaxis, coagulopathy, pancreatitis, thrombosis, and hepatic toxicity. Plasmapheresis can sometimes be appropriate to manage an overdose of drugs that circulate in the plasma compartment. We have reported plasmapheresis treatment of fulminant hepatitis in a patient with ALL after l-asparaginase treatment. © 2013 Elsevier Ltd.
dc.identifier.DOI-ID10.1016/j.transci.2013.06.010
dc.identifier.issn18781683
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/17261
dc.language.isoEnglish
dc.subjectAntineoplastic Agents
dc.subjectAsparaginase
dc.subjectDrug-Induced Liver Injury
dc.subjectFemale
dc.subjectHumans
dc.subjectLiver Failure, Acute
dc.subjectMiddle Aged
dc.subjectPlasma Exchange
dc.subjectPrecursor Cell Lymphoblastic Leukemia-Lymphoma
dc.subjectFulminant hepatic failure
dc.subjectl-Asparaginase
dc.subjectPlasmapheresis
dc.subjectasparaginase
dc.subjectdaunorubicin
dc.subjectprednisone
dc.subjectvincristine
dc.subjectantineoplastic agent
dc.subjectasparaginase
dc.subjectacute lymphoblastic leukemia
dc.subjectadult
dc.subjectarticle
dc.subjectbilirubin blood level
dc.subjectbone marrow biopsy
dc.subjectcancer combination chemotherapy
dc.subjectcase report
dc.subjectdrug dose reduction
dc.subjectfatigue
dc.subjectfemale
dc.subjectfever
dc.subjecthepatitis
dc.subjecthuman
dc.subjectplasmapheresis
dc.subjectside effect
dc.subjecttreatment response
dc.subjectacute liver failure
dc.subjectacute lymphoblastic leukemia
dc.subjectchemically induced disorder
dc.subjectfulminant hepatic failure
dc.subjectl-Asparaginase
dc.subjectmiddle aged
dc.subjecttoxic hepatitis
dc.titleAn experience with plasma exhcange treatment of acute lymphoblastic leukemia in a case with fulminant hepatitis related to l-asparaginase
dc.typeArticle

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