Synthesis and characterization of cerium- and gallium-containing borate bioactive glass scaffolds for bone tissue engineering

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dc.contributor.authorDeliormanlı A.M.
dc.date.accessioned2024-07-22T08:13:45Z
dc.date.available2024-07-22T08:13:45Z
dc.date.issued2015
dc.description.abstractBioactive glasses are widely used in biomedical applications due to their ability to bond to bone and even to soft tissues. In this study, borate based (13-93B3) bioactive glass powders containing up to 5 wt% Ce2O3 and Ga2O3 were prepared by the melt quench technique. Cerium (Ce+3) and gallium (Ga+3) were chosen because of their low toxicity associated with bacteriostatic properties. Bioactive glass scaffolds were fabricated using the polymer foam replication method. In vitro degradation and bioactivity of the scaffolds were evaluated in SBF under static conditions. Results revealed that the cerium- and gallium-containing borate glasses have much lower degradation rates compared to the bare borate glass 13-93B3. In spite of the increased chemical durability, substituted glasses exhibited a good in vitro bioactive response except when the Ce2O3 content was 5 wt%. Taking into account the high in vitro hydroxyapatite forming ability, borate glass scaffolds containing Ce+3 and Ga+3 therapeutic ions are promising candidates for bone tissue engineering applications. © 2015, Springer Science+Business Media New York.
dc.identifier.DOI-ID10.1007/s10856-014-5368-0
dc.identifier.issn09574530
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/16398
dc.language.isoEnglish
dc.publisherKluwer Academic Publishers
dc.subjectBody Fluids
dc.subjectBone Substitutes
dc.subjectBorates
dc.subjectCerium
dc.subjectDurapatite
dc.subjectEquipment Design
dc.subjectEquipment Failure Analysis
dc.subjectGallium
dc.subjectGlass
dc.subjectHardness
dc.subjectMaterials Testing
dc.subjectTissue Engineering
dc.subjectTissue Scaffolds
dc.subjectBioactive glass
dc.subjectBiodegradation
dc.subjectCerium compounds
dc.subjectDegradation
dc.subjectHydroxyapatite
dc.subjectMedical applications
dc.subjectScaffolds (biology)
dc.subjectTissue
dc.subjectcerium containing borate glass
dc.subjectgallium containing borate glass
dc.subjectglass
dc.subjecthydroxyapatite
dc.subjectunclassified drug
dc.subjectbone prosthesis
dc.subjectboric acid
dc.subjectceric oxide
dc.subjectcerium
dc.subjectgallium
dc.subjectgallium oxide
dc.subjectglass
dc.subjectBacteriostatic properties
dc.subjectBiomedical applications
dc.subjectBone tissue engineering
dc.subjectChemical durability
dc.subjectDegradation rate
dc.subjectReplication method
dc.subjectStatic conditions
dc.subjectSynthesis and characterizations
dc.subjectArticle
dc.subjectbiological activity
dc.subjectbone tissue
dc.subjectdegradation
dc.subjectfoam
dc.subjecthuman
dc.subjecthuman tissue
dc.subjectin vitro study
dc.subjectpriority journal
dc.subjectsynthesis
dc.subjecttissue engineering
dc.subjectbody fluid
dc.subjectbone prosthesis
dc.subjectchemistry
dc.subjectdevice failure analysis
dc.subjectdevices
dc.subjectequipment design
dc.subjecthardness
dc.subjectmaterials testing
dc.subjecttissue engineering
dc.subjecttissue scaffold
dc.subjectGallium compounds
dc.titleSynthesis and characterization of cerium- and gallium-containing borate bioactive glass scaffolds for bone tissue engineering
dc.typeArticle

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