The resistance of Pseudomonas aeruginosa strains to fluoroquinolone group of antibiotics
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Date
2004
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Abstract
Fluoroquinolones are antibiotics that are very effective against many gram negative microorganisms, including P. aeruginosa. However, resistance to these antibiotics has been reported in recent years as well. In this study, the sensivity of 136 P. aeruginosa strains, isolated from various clinical materials, to fluoroquinolones has been investigated. The lowest resistance rate was in ciprofloxacin with 12.5%. The resistance rates of the others were as follows: norfloxacin 14.7%, levofloxacin 16.9%, ofloxacin 19.9% and pefloxacin 28.7%. The 88.2% of the resistant strains to all fluoroquinolones were originated from intensive care unit.
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ciprofloxacin , levofloxacin , norfloxacin , ofloxacin , pefloxacin , quinoline derived antiinfective agent , antibiotic resistance , antibiotic sensitivity , article , bacterial strain , bacterium isolation , chi square test , controlled study , drug efficacy , Fisher exact test , Gram negative bacterium , intensive care unit , nonhuman , Pseudomonas aeruginosa