Serum levels of trace elements in patients with prostate cancer
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Date
2014
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Abstract
Background: Trace elements are major components of biological structures; however, excessive levels of these elements can be toxic. Materials and Methods: In the present study, serum levels of trace elements were measured in 30 patients with newly diagnosed as prostate cancer and 32 healthy volunteer by using furnace atomic absorption spectrophotometry. Results: It was found that there was an increase in serum levels of Co, Cu, Mg and Pb (p<0.05), whereas a decrease in serum levels of Fe, Mn, and Zn levels in patients with prostate cancer (p<0.05). Conclusions: These changes may be important in the pathogenesis of prostate cancers; however, further prospective studies are needed to identify relationships between prostate cancer and trace elements.
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Keywords
Aged , Case-Control Studies , Humans , Male , Prognosis , Prostate , Prostatic Neoplasms , Spectrophotometry, Atomic , Trace Elements , Tumor Markers, Biological , trace element , tumor marker , aged , atomic absorption spectrometry , blood , case control study , comparative study , human , male , metabolism , prognosis , prostate , Prostatic Neoplasms