Wound Healing and Microenvironment
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Date
2018
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Abstract
The wound healing process includes activation of signaling pathways that work together to restore a tissue microenvironment consisting of cells and extracellular matrix (ECM) with enzymes, cytokines, and growth factors. Wound healing consists of a dynamic process including various overlapping stages that include hemostasis and inflammation, cell proliferation, and maturation together with remodeling. In this chapter, we focus on wound healing types and the importance of the microenvironment. We then discuss the mechanism of wound healing and the interactions between molecules, cells, and extracellular matrix in the microenvironment during wound healing. © 2018 John Wiley & Sons, Inc. All rights reserved.