Functional parameters and affecting factors in post-COVID period; [Post-COVID dönemde fonksiyonel parametreler ve etkileyen faktörler]
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2023
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Abstract
Introduction: Post-COVID period is considered to be 12 weeks after the COVID-19 infection. Patients in the post-COVID period may have prolonged or newly developed symptoms. Depending on the prolonged effects of the disease, respiratory and functional parameters may be affected. The aim of the study is to investigate the effect of COVID-19 infection on respiratory and functional parameters in the post-COVID period. Materials and Methods: A cross-sectional study was conducted to evaluate the functional parameters of patients with COVID-19 in the post-COVID peri-od. Subjects with a history of microbiologically proven COVID-19 infection were evaluated with 6-minute walk test results, Borg, and MRC results at least 12 weeks after COVID-19 infection. The relationship between demographic characteristics, comorbidities, vaccination status, and severity of disease with 6-minute walk test results and dyspnea scales in the post-COVID period was investigated. Results: Two hundred seventeen patients were included in the study. The mean age of the patients was 48.6 ± 14.9 years and 126 (58.1%) of them were fema-le. 142 (65.4%) of the patients were completely vaccinated against COVID-19 and 75 (34.6%) patients were incompletely vaccinated or unvaccinated. 158 (72.8%) patients had mild disease, 51 (23.5%) patients had moderate disease, and eight (3.7%) patients had severe disease. Those with a history of moderate or severe disease had significantly worsened functional parameters in the post-COVID period compared to those with mild COVID-19. The Borg scale and MRC dyspnea scale values were significantly higher in women (p= 0.008, p= 0.002, respectively). Functional parameters of those who were completely vaccinated against COVID-19 and those who were incompletely or unvaccinated individuals in the post-COVID period were similar. Conclusion: The functional parameters of people with moderate or severe COVID-19 disease were found to be significantly impaired in the post-COVID period. While the effect of smoking and vaccination status on functional parameters in the post-COVID period could not be demonstrated, disease severity and accompanying comorbidity were found to be effective. © 2023 by Tuberculosis and Thorax.
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Adult , COVID-19 , Cross-Sectional Studies , Dyspnea , Female , Humans , Male , Middle Aged , Smoking , adult , arterial pressure , arthralgia , Article , asthma , body mass , breathing rate , cardiopulmonary function , chi square test , chronic obstructive lung disease , clinical feature , comorbidity , connective tissue disease , coronary artery disease , coughing , cross-sectional study , demographics , diabetes mellitus , disease severity , dyspnea , fatigue , female , fever , fibrosing alveolitis , functional status , headache , heart rate , Horowitz index , human , hypertension , immunization , interstitial lung disease , long COVID , major clinical study , male , Medical Research Council Dyspnea Scale , middle aged , oxygen saturation , oxygen therapy , physical activity , regression analysis , respiratory tract infection , respiratory tract parameters , six minute walk test , smoking , sore throat , vaccination , coronavirus disease 2019 , dyspnea