Comparison of infants and children with urolithiasis: a large case series

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dc.contributor.authorBaştuğ F.
dc.contributor.authorAğbaş A.
dc.contributor.authorTülpar S.
dc.contributor.authorYıldırım Z.N.Y.
dc.contributor.authorÇiçek N.
dc.contributor.authorGünay N.
dc.contributor.authorGemici A.
dc.contributor.authorÇelik B.
dc.contributor.authorDelebe E.Ö.Ç.
dc.contributor.authorNalçacıoğlu H.
dc.contributor.authorYılmaz A.
dc.contributor.authorGökçe İ.
dc.contributor.authorDemircin G.
dc.contributor.authorHacıhamdioğlu D.Ö.
dc.contributor.authorYılmaz K.
dc.contributor.authorAtmış B.
dc.contributor.authorYılmaz E.K.
dc.contributor.authorErtan P.
dc.contributor.authorDursun İ.
dc.contributor.authorAksu B.
dc.contributor.authorAkbulut B.B.
dc.contributor.authorDöven S.S.
dc.contributor.authorÖner N.
dc.contributor.authorYel S.
dc.contributor.authorElmacı A.M.
dc.contributor.authorAtikel Y.Ö.
dc.contributor.authorErfidan G.
dc.contributor.authorUysal B.
dc.contributor.authorBıyıklı N.
dc.contributor.authorYazıcıoğlu B.
dc.contributor.authorKüçük N.
dc.contributor.authorÇomak E.
dc.contributor.authorSever F.L.
dc.contributor.authorAkil İ.
dc.contributor.authorAksoy Ö.
dc.contributor.authorAlpay H.
dc.date.accessioned2024-07-22T08:04:15Z
dc.date.available2024-07-22T08:04:15Z
dc.date.issued2022
dc.description.abstractWe evaluated the demographic features, etiologic risk factors, treatment strategies, and outcome of the infants and children with urolithiasis (UL). A retrospective multicenter study was conducted including 23 Pediatric Nephrology centers in Turkey. The medical records of 2513 children with UL were reviewed. One thousand, three hundred and four boys and 1209 girls (1.1:1) were reported. The mean age at diagnosis was 39.5 ± 35 months (0.4–231 months), and 1262 patients (50.2%) were in the first year of life (infants). Most of the cases with infantile UL were diagnosed incidentally. Microlithiasis (< 3 mm) was found in 794 patients (31.6%), and 64.5% of the patients with microlithiasis were infants. Stones were located in the pelvis-calyces in 63.2% (n: 1530) of the cases. The most common stone type was calcium oxalate (64.6%). Hypocitraturia was the most common metabolic risk factor (MRF) in children older than 12 months, but in infancy, hypercalciuria was more common. Fifty-five percent of the patients had received at least one medical treatment, mostly potassium citrate. At the end of a year’s follow-up, most of the patients with microlithiasis (85%) showed spontaneous remission. The rate of spontaneous stone resolution in infants was higher than in children. Spontaneous remission rate was higher in cases with MRF (− ) stones than in MRF (+) stones. However, remission rate with medical treatment was higher in cases with MRF (+) stones. This study represents the results of a large series of infants and children with UL and showed that there are several differences such as underlying metabolic and anatomic abnormalities, clinical course, and stone remission rates between infants and children with urinary stone disease. © 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
dc.identifier.DOI-ID10.1007/s00240-022-01327-0
dc.identifier.issn21947228
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/12620
dc.language.isoEnglish
dc.publisherSpringer Science and Business Media Deutschland GmbH
dc.subjectChild
dc.subjectFemale
dc.subjectHumans
dc.subjectHypercalciuria
dc.subjectInfant
dc.subjectMale
dc.subjectPotassium Citrate
dc.subjectRemission, Spontaneous
dc.subjectRetrospective Studies
dc.subjectRisk Factors
dc.subjectUrinary Calculi
dc.subjectUrolithiasis
dc.subjectcitrate potassium
dc.subjectcitrate potassium
dc.subjectArticle
dc.subjectcase study
dc.subjectchild
dc.subjectconservative treatment
dc.subjectdemographics
dc.subjectdemography
dc.subjectetiology
dc.subjectextracorporeal shock wave lithotripsy
dc.subjectfemale
dc.subjectfollow up
dc.subjecthuman
dc.subjecthypercalciuria
dc.subjecthypocitraturia
dc.subjectinfant
dc.subjectkidney calyx
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmedical record
dc.subjectmedical record review
dc.subjectmicrolithiasis
dc.subjectmulticenter study
dc.subjectnephrology
dc.subjectoutcome assessment
dc.subjectpelvis
dc.subjectremission
dc.subjectretrospective study
dc.subjectrisk assessment
dc.subjectrisk factor
dc.subjectstone dissolution
dc.subjecttreatment outcome
dc.subjecttreatment planning
dc.subjectTurkey (republic)
dc.subjecturolithiasis
dc.subjectclinical trial
dc.subjectcomplication
dc.subjecturolithiasis
dc.titleComparison of infants and children with urolithiasis: a large case series
dc.typeArticle

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