The ureteral diameter ratio as a predictive factor in renal scarring associated with primary vesicoureteral reflux

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dc.contributor.authorAkyol Onder E.N.
dc.contributor.authorEnsari E.
dc.contributor.authorOzkol M.
dc.contributor.authorYilmaz O.
dc.contributor.authorTaneli C.
dc.contributor.authorErtan P.
dc.date.accessioned2024-07-22T08:02:32Z
dc.date.available2024-07-22T08:02:32Z
dc.date.issued2023
dc.description.abstractIntroduction: The ureteral diameter ratio (UDR) is reported to be effective in predicting the outcomes of vesicoureteral reflux (VUR) in several studies. Objective: The objective of the current study was to compare the risk of scarring in patients with VUR relative to UDR and the VUR grade. We also aimed to demonstrate other associated risk factors in scarring and investigate the long-term complications of VUR and their relationship with UDR. Study design: Patients diagnosed with primary VUR were retrospectively enrolled in the study. UDR was calculated by dividing the largest ureteral diameter (UD) by the distance between L1-L3 vertebral bodies. Demographic and clinical data, laterality, VUR grade, UDR, delayed upper tract drainage on voiding cystourethrogram, recurrent urinary tract infections (UTI), and long-term complications of VUR were compared between the patients with and without renal scars. Results: A total of 127 patients and 177 renal units were included in the study. There was a significant difference between the patients with and without renal scars according to age at diagnosis, bilaterality, reflux grade, UDR, recurrent UTI, bladder bowel dysfunction, hypertension, decreased estimated glomerular filtration rate, and proteinuria. The logistic regression analysis revealed that UDR had the highest odds ratio among the factors affecting scarring in VUR. Discussion: VUR grading based on the evaluation of the upper urinary tract is one of the most important predictors for treatment options and prognosis. However, it is more likely to reflect ureterovesical junctional anatomy and function, which play a crucial role in the pathogenesis of VUR. Conclusion: UDR measurement seems to be an objective method that can help clinicians predict renal scarring in patients with primary VUR. [Table presented] © 2023 Journal of Pediatric Urology Company
dc.identifier.DOI-ID10.1016/j.jpurol.2023.03.015
dc.identifier.issn14775131
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11880
dc.language.isoEnglish
dc.publisherElsevier Ltd
dc.subjectCicatrix
dc.subjectHumans
dc.subjectInfant
dc.subjectRetrospective Studies
dc.subjectUreter
dc.subjectUreteroscopy
dc.subjectUrinary Tract Infections
dc.subjectVesico-Ureteral Reflux
dc.subjectcreatinine
dc.subjectdipeptidyl carboxypeptidase inhibitor
dc.subjectsuccimer
dc.subjecttechnetium 99m
dc.subjectArticle
dc.subjectchild
dc.subjectcohort analysis
dc.subjectcontrolled study
dc.subjectcreatinine blood level
dc.subjectdemographics
dc.subjectdiagnosis time
dc.subjectdisease classification
dc.subjectestimated glomerular filtration rate
dc.subjectfemale
dc.subjectfirst lumbar vertebra
dc.subjecthealth data
dc.subjecthuman
dc.subjecthypertension
dc.subjectkidney scar
dc.subjectlogistic regression analysis
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmicturition cystourethrography
dc.subjectmicturition disorder
dc.subjectonset age
dc.subjectpredictive value
dc.subjectpreschool child
dc.subjectproteinuria
dc.subjectreceiver operating characteristic
dc.subjectrecurrent disease
dc.subjectretrospective study
dc.subjectrisk factor
dc.subjectschool child
dc.subjectsecond lumbar vertebra
dc.subjectthird lumbar vertebra
dc.subjectureteral diameter ratio
dc.subjecturinary tract infection
dc.subjecturologic examination
dc.subjectvertebra body
dc.subjectvesicoureteral reflux
dc.subjectinfant
dc.subjectpathology
dc.subjectprocedures
dc.subjectscar
dc.subjectureter
dc.subjectureteroscopy
dc.subjecturinary tract infection
dc.subjectvesicoureteral reflux
dc.titleThe ureteral diameter ratio as a predictive factor in renal scarring associated with primary vesicoureteral reflux
dc.typeArticle

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