Subanalgesic doses of ketamine and morphine but not morphine alone, prolong the sensory block time of hyperbaric bupivacaine in unilateral spinal anaesthesia

dc.contributor.authorYentür E.A.
dc.contributor.authorTok D.
dc.contributor.authorKeleş G.T.
dc.contributor.authorToprak V.
dc.contributor.authorAslan F.
dc.date.accessioned2024-07-22T08:24:20Z
dc.date.available2024-07-22T08:24:20Z
dc.date.issued2004
dc.description.abstractAim: In this study, we aimed to compare the sensory and motor effects of a subanalgesic dose of morphine and morphine + ketamine added to 5% hyperbaric bupivacaine (HB) in unilateral spinal anaesthesia. Methods: 45 patients were randomly assigned to one of three groups. The first group received 1.5 ml 0.5% HB + 0.2 ml saline; the second group received 1.5 ml 0.5% HB + 0.1 ml morphine (0.1 mg) + 0.1 ml saline; the third group received 1.5 ml 0.5% HB + 0.1 ml ketamine (0.5 mg) + 0.1 ml morphine (0.1 mg). Maximum block levels, time to reach that level, time to reach T10 level and block levels after 120 min were recorded. Results: Maximum sensory and motor block levels, time to reach these levels and time to reach T10 level were similar in all three groups, but there was less regression of sensory block level in the third group than in the other two groups. Conclusion: Subanalgesic doses of morphine and ketamine added to 0.5% HB extended the sensory block period but not the motor block in unilateral spinal anaesthesia.
dc.identifier.DOI-ID10.1163/1568569042664495
dc.identifier.issn01691112
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19934
dc.language.isoEnglish
dc.subjectbupivacaine
dc.subjectketamine
dc.subjectmorphine
dc.subjectadult
dc.subjectanesthesia level
dc.subjectarticle
dc.subjectclinical article
dc.subjectclinical trial
dc.subjectcontrolled clinical trial
dc.subjectcontrolled study
dc.subjectdose time effect relation
dc.subjectdrug potentiation
dc.subjectfemale
dc.subjecthuman
dc.subjectmale
dc.subjectnerve block
dc.subjectorthopedic surgery
dc.subjectspinal anesthesia
dc.titleSubanalgesic doses of ketamine and morphine but not morphine alone, prolong the sensory block time of hyperbaric bupivacaine in unilateral spinal anaesthesia
dc.typeArticle

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