Acute pancreatitis in Turkey: Results of a nationwide multicenter study

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dc.contributor.authorKöksal A.Ş.
dc.contributor.authorTozlu M.
dc.contributor.authorSezgin O.
dc.contributor.authorOğuz D.
dc.contributor.authorKalkan İ.H.
dc.contributor.authorAltıntaş E.
dc.contributor.authorYaraş S.
dc.contributor.authorBilgiç Y.
dc.contributor.authorYıldırım A.E.
dc.contributor.authorBarutçu S.
dc.contributor.authorHakim G.D.
dc.contributor.authorSoytürk M.
dc.contributor.authorBengi G.
dc.contributor.authorÖzşeker B.
dc.contributor.authorYurci A.
dc.contributor.authorKoç D.Ö.
dc.contributor.authorİrak K.
dc.contributor.authorKasap E.
dc.contributor.authorCindoruk M.
dc.contributor.authorOruç N.
dc.contributor.authorÜnal N.G.
dc.contributor.authorŞen İ.
dc.contributor.authorGökden Y.
dc.contributor.authorSaruç M.
dc.contributor.authorÜnal H.
dc.contributor.authorEminler A.T.
dc.contributor.authorToka B.
dc.contributor.authorBasır H.
dc.contributor.authorSağlam O.
dc.contributor.authorErgül B.
dc.contributor.authorGül Ö.
dc.contributor.authorBüyüktorun İ.
dc.contributor.authorÖzel M.
dc.contributor.authorŞair Ü.
dc.contributor.authorKösem G.
dc.contributor.authorNedirli F.
dc.contributor.authorTahtacı M.
dc.contributor.authorParlak E.
dc.date.accessioned2024-07-22T08:01:21Z
dc.date.available2024-07-22T08:01:21Z
dc.date.issued2024
dc.description.abstractBackground: Acute pancreatitis (AP) is the most common gastrointestinal disease requiring hospitalization, with significant mortality and morbidity. We aimed to evaluate the clinical characteristics of AP and physicians’ compliance with international guidelines during its management. Methods: All patients with AP who were hospitalized at 17 tertiary centers in Turkey between April and October 2022 were evaluated in a prospective cohort study. Patients with insufficient data, COVID-19 and those aged below 18 years were excluded. The definitions were based on the 2012 revised Atlanta criteria. Results: The study included 2144 patients (median age:58, 52 % female). The most common etiologies were biliary (n = 1438, 67.1 %), idiopathic (n = 259, 12 %), hypertriglyceridemia (n = 128, 6 %) and alcohol (n = 90, 4.2 %). Disease severity was mild in 1567 (73.1 %), moderate in 521 (24.3 %), and severe in 58 (2.6 %) patients. Morphology was necrotizing in 4.7 % of the patients. The overall mortality rate was 1.6 %. PASS and BISAP had the highest accuracy in predicting severe pancreatitis on admission (AUC:0.85 and 0.81, respectively). CT was performed in 61 % of the patients, with the majority (90 %) being within 72 h after admission. Prophylactic NSAIDs were not administered in 44 % of the patients with post-ERCP pancreatitis (n = 86). Antibiotics were administered to 53.7 % of the patients, and 38 % of those received them prophylactically. Conclusions: This prospective study provides an extensive report on clinical characteristics, management and outcomes of AP in real-world practice. Mortality remains high in severe cases and physicians’ adherence to guidelines during management of the disease needs improvement in some aspects. © 2023 IAP and EPC
dc.identifier.DOI-ID10.1016/j.pan.2023.10.005
dc.identifier.issn14243903
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11408
dc.language.isoEnglish
dc.publisherElsevier B.V.
dc.subjectAcute Disease
dc.subjectAged
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectPancreatitis
dc.subjectProspective Studies
dc.subjectRetrospective Studies
dc.subjectSeverity of Illness Index
dc.subjectTurkey
dc.subjectamylase
dc.subjectanalgesic agent
dc.subjectantibiotic agent
dc.subjectantihypertensive agent
dc.subjectazathioprine
dc.subjectbilirubin
dc.subjectC reactive protein
dc.subjectcreatinine
dc.subjecterythromycin estolate
dc.subjectglucose
dc.subjectnitrogen
dc.subjectnonsteroid antiinflammatory agent
dc.subjectoral antidiabetic agent
dc.subjecttriacylglycerol lipase
dc.subjecturea
dc.subjectabdominal pain
dc.subjectaccuracy
dc.subjectacute hemorrhagic pancreatitis
dc.subjectacute pancreatitis
dc.subjectadult
dc.subjectaged
dc.subjectamylase blood level
dc.subjectantibiotic therapy
dc.subjectArticle
dc.subjectbilirubin blood level
dc.subjectbody mass
dc.subjectcardiovascular disease
dc.subjectcerebrovascular accident
dc.subjectchronic kidney failure
dc.subjectchronic obstructive lung disease
dc.subjectclinical feature
dc.subjectcohort analysis
dc.subjectcolon ischemia
dc.subjectcommon bile duct stone
dc.subjectcomputer assisted tomography
dc.subjectcreatinine blood level
dc.subjectcurrent smoker
dc.subjectdiabetes mellitus
dc.subjectdisease severity
dc.subjectfalse aneurysm
dc.subjectfemale
dc.subjectfever
dc.subjectheart failure
dc.subjecthospital admission
dc.subjecthospitalization
dc.subjecthuman
dc.subjecthypertension
dc.subjecthypertriglyceridemia
dc.subjectkidney failure
dc.subjectlaboratory test
dc.subjectleukocyte count
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmedical history
dc.subjectmedical record review
dc.subjectmortality
dc.subjectmortality rate
dc.subjectmulticenter study
dc.subjectobesity
dc.subjectobservational study
dc.subjectobstructive jaundice
dc.subjectpancreas necrosis
dc.subjectpatient history of cholecystectomy
dc.subjectpercutaneous drainage
dc.subjectprospective study
dc.subjectpylorus stenosis
dc.subjectrespiratory failure
dc.subjectsex difference
dc.subjectsplanchnic vein thrombosis
dc.subjecttriacylglycerol level
dc.subjecttriacylglycerol lipase blood level
dc.subjectTurkey (republic)
dc.subjecturea nitrogen blood level
dc.subjectacute disease
dc.subjectclinical trial
dc.subjectpancreatitis
dc.subjectretrospective study
dc.subjectseverity of illness index
dc.subjectturkey (bird)
dc.titleAcute pancreatitis in Turkey: Results of a nationwide multicenter study
dc.typeArticle

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