Fluorescein dye disappearance test in patients with different degrees of epiphora

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dc.contributor.authorToprak A.B.
dc.contributor.authorErkin E.F.
dc.contributor.authorKayikçioǧlu Ö.
dc.contributor.authorSeymenoǧlu G.
dc.contributor.authorGüler C.
dc.contributor.authorUnlu H.H.
dc.date.accessioned2024-07-22T08:25:11Z
dc.date.available2024-07-22T08:25:11Z
dc.date.issued2002
dc.description.abstractPURPOSE. To assess the diagnostic efficacy of a modification of the fluorescein dye disappearance test (DDT) in patients with different degrees of epiphora. METHODS. DDT was performed by instilling a drop of 2% fluorescein in the eye. Schirmer tear test strips were placed in the lower conjunctival fornix, after 3 and 10 minutes. The colour dilution on the strips was compared to a scale with known standards and the most closely comparable colour dilution was chosen and recorded as the visual scale test (VST) grade of the strip. The grey-scale value (GV) of each strip was calculated by computer image analysis. The control group comprised 44 patients, mean age 44.8 years (SD 7.5, range 30-60). There were 13 patients in group 1 with moderate epiphora; mean age was 44.2 years (SD 9.5, range 30-60). There were 17 patients in group 2 with severe epiphora; mean age was 48.3 years (SD 7.7, range 37- 60). RESULTS. VST and GV differed significantly between controls and group 1 patients at 3 minutes (p=0.002, p=0.001), and between controls and group 2 patients at 3 minutes (p<0.001, p<0.001). There was no difference between groups 1 and 2 patients in VST and GV at 3 minutes. The differences were highly significant between controls and group 1 at 10 minutes (p=0.001, p=0.007), and between controls and group 2 at 10 minutes (p<0.001, p<0.001). The differences in GV and VST between groups 1 and 2 were significant at 10 minutes (p=0.026, p=0.018). CONCLUSIONS. This modified DDT permits identification of different degrees of epiphora in a non-invasive manner, it can therefore be used to evaluate the outcome of different treatment strategies.
dc.identifier.DOI-ID10.1177/112067210201200503
dc.identifier.issn11206721
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20302
dc.language.isoEnglish
dc.publisherWichtig Editore s.r.l.
dc.subjectfluorescein
dc.subjectadult
dc.subjectarticle
dc.subjectcalculation
dc.subjectclinical article
dc.subjectcolor
dc.subjectcomputer analysis
dc.subjectcontrolled study
dc.subjectcorrelation analysis
dc.subjectdiagnostic accuracy
dc.subjectdisease classification
dc.subjectdisease severity
dc.subjectepiphora
dc.subjecthuman
dc.subjectindicator dilution curve
dc.subjectintermethod comparison
dc.subjectoutcomes research
dc.subjectpriority journal
dc.subjectSchirmer test
dc.subjectstatistical significance
dc.subjecttime
dc.titleFluorescein dye disappearance test in patients with different degrees of epiphora
dc.typeArticle

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