Histopathological Results of Conjunctival Masses with Suspected Malignancy Based on Slit-lamp Biomicroscopy

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dc.contributor.authorErdogan M.
dc.contributor.authorMayali H.
dc.contributor.authorMalgaz S.
dc.contributor.authorAltinisik M.
dc.contributor.authorIlker S.S.
dc.date.accessioned2024-07-22T08:02:42Z
dc.date.available2024-07-22T08:02:42Z
dc.date.issued2023
dc.description.abstractObjective: To evaluate the histopathological results of conjunctival masses suspected to be malignant based on biomicroscopic examination. Study Design: Observational study. Place and Duration of the Study: Department of Ophthalmology, Celal Bayar University, Hafsa Sultan Hospital, Manisa, Turkiye, from November 2013 to February 2021. Methodology: Patients who underwent excision for the diagnosis and treatment of conjunctival surface masses with clinical suspicion of malignancy were evaluated retrospectively. The masses were categorised as benign, premalignant, and malignant lesions according to the histopathological results. The distribution of conjunctival masses was analysed according to patients’ gender and age groups. Results: The study included 98 conjunctival masses in 98 patients (57.1% men, mean age 48.6±21.85 years). On pathological examination, 63 of the masses were found to be benign (64.3%), 22 were premalignant (22.4%), and 13 were malignant (13.3%). The most common benign lesion was nevus (n=21, 21.4%). All detected premalignant lesions were conjunctival intraepithelial neoplasms (CIN), detected in 22 patients (22.4%). Of these, 13 patients (13.3%) had carcinoma in situ (CIN III). Thirteen (13.3%) of the masses were malignant, the most common being squamous cell carcinoma (n=10, 10.2%). The frequency of premalignant and malignant lesions increased with age (p<0.001). There was no statistical relationship between malignancy and gender (p=0.619). Conclusion: Most conjunctival masses in this series were benign, with nevi being the most common. The most common premalignant and malignant lesions were intraepithelial neoplasia and squamous cell carcinoma, respectively. Malignant conjunctival lesions were more common in older patients. © 2023 College of Physicians and Surgeons Pakistan. All rights reserved.
dc.identifier.DOI-ID10.29271/jcpsp.2023.08.932
dc.identifier.issn1022386X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11970
dc.language.isoEnglish
dc.publisherCollege of Physicians and Surgeons Pakistan
dc.rightsAll Open Access; Gold Open Access
dc.subjectAdult
dc.subjectAged
dc.subjectCarcinoma in Situ
dc.subjectCarcinoma, Squamous Cell
dc.subjectConjunctival Neoplasms
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectNevus, Pigmented
dc.subjectPrecancerous Conditions
dc.subjectRetrospective Studies
dc.subjectSkin Neoplasms
dc.subjectadult
dc.subjectArticle
dc.subjectcarcinoma in situ
dc.subjectconjunctiva tumor
dc.subjectconjunctival intraepithelial neoplasm
dc.subjectconjunctival nevus
dc.subjectdemographics
dc.subjectexcision
dc.subjecteye cancer
dc.subjectfemale
dc.subjectfrequency
dc.subjectgender
dc.subjectgroups by age
dc.subjecthistopathology
dc.subjecthuman
dc.subjecthuman tissue
dc.subjectintraepithelial neoplasia
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmiddle aged
dc.subjectnevus
dc.subjectobservational study
dc.subjectretrospective study
dc.subjectslit lamp microscopy
dc.subjectsquamous cell carcinoma
dc.subjectTurkey (republic)
dc.subjectaged
dc.subjectcarcinoma in situ
dc.subjectconjunctiva tumor
dc.subjectpathology
dc.subjectpigmented nevus
dc.subjectprecancer
dc.subjectskin tumor
dc.subjectsquamous cell carcinoma
dc.titleHistopathological Results of Conjunctival Masses with Suspected Malignancy Based on Slit-lamp Biomicroscopy
dc.typeArticle

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