Relation between nocturnal decline in blood pressure and choroidal thickness: a comparative analysis in dipper vs. non-dipper hypertensive patients

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dc.contributor.authorTas S.
dc.contributor.authorAltinisik M.
dc.contributor.authorTas Ü.
dc.date.accessioned2024-07-22T08:05:56Z
dc.date.available2024-07-22T08:05:56Z
dc.date.issued2021
dc.description.abstractPurpose To compare choroidal thickness (ChT) and echocardiographical changes in patients with dipper and non-dipper systemic arterial hypertension (HT). Methods Patients with HT were evaluated in two groups according to the 24-hour ambulatory BP monitoring. Compared to day-time values, those whose night-time SBP decreased ≥10% were defined as dippers, and those whose SBP decreased <10% were defined as non-dippers. Transthoracic echocardiography was conducted in all patients. ChT and central macular thickness were measured with spectral-domain optical coherence tomography. ChT was obtained at the subfoveal, 1500 µm nasal and temporal to the fovea. Results Thirty non-dipper (18 females and 12 males) and 23 dipper (16 females and seven males) hypertensive patients were recruited. Sex distribution and the mean age were similar between the groups (P = 0.472; P = 0.12). Disease duration was longer in the non-dipper group (8 ± 3.39 vs. 4.96 ± 1.19 years, P = 0.001). The non-dipper group had lower ChT in subfoveal and temporal locations (P = 0.02 and 0.03, respectively) and higher left atrial volume index (LAVI) and pulmonary valve maximum flow (PV-max; P < 0.001). The night-time SBP was negatively correlated with ChT (P = 0.048) and positive correlated with LAVI and PV-max (P < 0.05). However those correlations were not significant when were controlled by the possible confounding factors as disease duration, age and gender. Conclusion Non-dipper HT patients may have thinner choroid than dippers due to longer duration of HT and higher ambulatory BP levels. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
dc.identifier.DOI-ID10.1097/MBP.0000000000000502
dc.identifier.issn13595237
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13300
dc.language.isoEnglish
dc.publisherLippincott Williams and Wilkins
dc.subjectBlood Pressure
dc.subjectBlood Pressure Monitoring, Ambulatory
dc.subjectChoroid
dc.subjectCircadian Rhythm
dc.subjectFemale
dc.subjectHumans
dc.subjectHypertension
dc.subjectMale
dc.subjectblood pressure
dc.subjectblood pressure monitoring
dc.subjectchoroid
dc.subjectcircadian rhythm
dc.subjectdiagnostic imaging
dc.subjectfemale
dc.subjecthuman
dc.subjecthypertension
dc.subjectmale
dc.titleRelation between nocturnal decline in blood pressure and choroidal thickness: a comparative analysis in dipper vs. non-dipper hypertensive patients
dc.typeArticle

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