Detection of permethrin resistance and phylogenetic clustering of turkish head lice (Pediculus humanus capitis; De Geer, 1767 populations

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dc.contributor.authorKarakuş M.
dc.contributor.authorAtıcı T.
dc.contributor.authorKarabela Ş.N.
dc.contributor.authorBaylan O.
dc.contributor.authorLimoncu M.E.
dc.contributor.authorBalcıoğlu İ.C.
dc.date.accessioned2024-07-22T08:07:32Z
dc.date.available2024-07-22T08:07:32Z
dc.date.issued2020
dc.description.abstractHead lice infestation caused by Pediculus humanus capitis De Geer, 1767 is one of the most common public health problems. The relationship between humans and head lice dates back millions of years ago that differentiated into different phylogenetic clades. Treatment of head lice infestation usually based on insecticide-based products, which promotes the resistance in the head lice populations. In the present study, we aimed to screen the presence of permethrin resistance among collected P. h. capitis specimens in Turkey. Three mutation sites (T917I, L920F, and M815I) were screened using real-time PCR and resistance was identified by melt analysis. Of the studied specimens, resistance allele frequency (RAF) was found 0.98 for T917I, 0.99 for L920F, and 1.00 for M815I. The phylogenetic study revealed that Clade A and Clade B are present and overlap in Turkey. The present study is first to screen the resistance among Turkish head lice specimens. To not stimulate the pyrethroids resistance in head lice populations, early detection of resistance is crucial and will help the health professionals to choose suitable formula in the treatment. We suggest that the resistance status needs to be screened in randomly selected populations before any treatment application is given. © 2020 Elsevier B.V.
dc.identifier.DOI-ID10.1016/j.actatropica.2020.105362
dc.identifier.issn0001706X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13983
dc.language.isoEnglish
dc.publisherElsevier B.V.
dc.subjectAnimals
dc.subjectChild
dc.subjectCluster Analysis
dc.subjectFemale
dc.subjectGene Frequency
dc.subjectHumans
dc.subjectInsecticide Resistance
dc.subjectInsecticides
dc.subjectLice Infestations
dc.subjectMale
dc.subjectPediculus
dc.subjectPermethrin
dc.subjectPhylogeny
dc.subjectReal-Time Polymerase Chain Reaction
dc.subjectTurkey
dc.subjectTurkey
dc.subjectPediculus
dc.subjectPediculus humanus
dc.subjectPediculus humanus capitis
dc.subjectpermethrin
dc.subjectinsecticide
dc.subjectpermethrin
dc.subjectdetection method
dc.subjectlouse
dc.subjectpermethrin
dc.subjectpesticide resistance
dc.subjectphylogenetics
dc.subjectpyrethroid
dc.subjectadult
dc.subjectArticle
dc.subjectcladistics
dc.subjectcontrolled study
dc.subjectcytb gene
dc.subjectgene
dc.subjectgene cluster
dc.subjectgene frequency
dc.subjectgenetic variability
dc.subjecthuman
dc.subjectnonhuman
dc.subjectnucleotide sequence
dc.subjectpediculosis capitis
dc.subjectPediculus humanus capitis
dc.subjectpesticide resistance
dc.subjectphylogeny
dc.subjectpopulation distribution
dc.subjectreal time polymerase chain reaction
dc.subjectTurkey (republic)
dc.subjectanimal
dc.subjectchild
dc.subjectcluster analysis
dc.subjectdrug effect
dc.subjectepidemiology
dc.subjectfemale
dc.subjectgenetics
dc.subjectinsecticide resistance
dc.subjectmale
dc.subjectparasitology
dc.subjectpediculosis
dc.subjectPediculus
dc.subjectphylogeny
dc.subjectturkey (bird)
dc.titleDetection of permethrin resistance and phylogenetic clustering of turkish head lice (Pediculus humanus capitis; De Geer, 1767 populations
dc.typeArticle

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