Phenolic composition, antioxidant and enzyme inhibitory activities of acetone, methanol and water extracts of Clinopodium vulgare L. subsp. vulgare L.

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dc.contributor.authorSarikurkcu C.
dc.contributor.authorOzer M.S.
dc.contributor.authorTepe B.
dc.contributor.authorDilek E.
dc.contributor.authorCeylan O.
dc.date.accessioned2024-07-22T08:12:32Z
dc.date.available2024-07-22T08:12:32Z
dc.date.issued2015
dc.description.abstractThe aim of this study is to evaluate the antioxidant and enzyme inhibitory activities of acetone, methanol and water extracts of Clinopodium vulgare L. subsp. vulgare L. as well as its phytochemical composition. Methanol extract was found rich in of phenolic compounds (44.42. mg GAEs/g extract) whereas the highest flavonoid content was determined in the water extract (40.20. mg REs/g extract). Methanol extract was also found rich in protocatechuic acid, (+)-catechin, chlorogenic acid, caffeic acid, ferulic acid, rosmarinic acid and apigenin. Data obtained from the phosphomolybdenum assay was found in correlation with those obtained from total phenolic assay. Methanol extract exhibited the highest activity (374.86. mmol TEs/g extract). In the case of chelating effect assay, acetone extract exhibited the highest activity. As observed in many previously reported studies, water extract exhibited the highest DPPH free radical scavenging activity (81.72. mg TEs/g extract). ABTS cation scavenging assay was resulted in the superiority of methanol extract (51.45. mg TEs/g extract). It also showed the strongest reducing power in CUPRAC and FRAP assays. Acetone extract exhibited remarkable inhibitory activity on acetylcholinesterase, butyrylcholinesterase and tyrosinase, while the highest α-amylase and α-glucosidase inhibitory activities were exhibited by methanol and water extracts. Total amounts of unsaturated fatty acids were determined as 51.15%. C18:1 ω9, C18:2 ω6 and C18:3 ω3 were determined in considerable quantities (23.93, 6.18 and 5.78%, respectively). © 2015 Elsevier B.V.
dc.identifier.DOI-ID10.1016/j.indcrop.2015.08.011
dc.identifier.issn09266690
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/16076
dc.language.isoEnglish
dc.publisherElsevier
dc.subjectClinopodium vulgare
dc.subjectAcetone
dc.subjectAntioxidants
dc.subjectAssays
dc.subjectChelation
dc.subjectEnzyme activity
dc.subjectEnzymes
dc.subjectFatty acids
dc.subjectFlavonoids
dc.subjectFree radicals
dc.subjectMethanol
dc.subjectPhenols
dc.subjectPlants (botany)
dc.subjectUnsaturated fatty acids
dc.subjectAnti-oxidant activities
dc.subjectClinopodium vulgare L. subsp. vulgare L
dc.subjectFatty acid composition
dc.subjectInhibitory activity
dc.subjectPhytochemical composition
dc.subjectantioxidant
dc.subjectbioassay
dc.subjectchemical composition
dc.subjectenzyme activity
dc.subjectfatty acid
dc.subjectherb
dc.subjectinhibitor
dc.subjectorganic compound
dc.subjectplant extract
dc.subjectExtraction
dc.titlePhenolic composition, antioxidant and enzyme inhibitory activities of acetone, methanol and water extracts of Clinopodium vulgare L. subsp. vulgare L.
dc.typeArticle

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