Xanthogranulomatous pyelonephritis due to calculi in a 5-year-old girl

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dc.contributor.authorÖnder E.N.A.
dc.contributor.authorÖzkol M.
dc.contributor.authorNeşe N.
dc.contributor.authorTaneli C.
dc.contributor.authorÖzünan İ.
dc.date.accessioned2024-07-22T08:07:58Z
dc.date.available2024-07-22T08:07:58Z
dc.date.issued2020
dc.description.abstractBackground. Xanthogranulomatous pyelonephritis is characterized by the inflammatory destruction of the renal parenchyma and intensive renal fibrosis. It is named because of its pathological appearance; that of its granulomatous inflammatory process with lipid-laden macrophages, which appear yellow, hence ‘xantho’ which is Greek for yellow. Xanthogranulomatous pyelonephritis is predominantly a disease of adults. In children it is diagnosed sporadically and is extremely rare in infants. The age of onset varies (21 days to 16 years), although 60-75% of cases have been diagnosed before 5 years of age. Recurrent urinary tract infections, obstructive nephropathy caused by renal calculus, malnutrition, abnormal lipid metabolism, altered immunologic response, lymphatic blockage, congenital urinary anomalies have been implicated in the etiology of xanthogranulomatous pyelonephritis in children. Case. We report an unusual case of xanthogranulomatous pyelonephritis in a 5-year-old girl and discuss its clinical features, histopathological findings and treatment. In this article, we also emphasized the importance of diagnostic imaging in urinary tract infections which enabled us not to miss the underlying kidney stone disease. Conclusion. Nephrolithiasis may lead to very serious conditions such as xanthogranulomatous pyelonephritis. This condition can be easily diagnosed by ultrasound, but if not detected, it can lead to complete loss of renal function as in the case. © 2020, Turkish Journal of Pediatrics. All rights reserved.
dc.identifier.DOI-ID10.24953/turkjped.2020.04.024
dc.identifier.issn00414301
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/14181
dc.language.isoEnglish
dc.publisherTurkish National Pediatric Society
dc.rightsAll Open Access; Gold Open Access
dc.subjectAdult
dc.subjectCalculi
dc.subjectChild
dc.subjectChild, Preschool
dc.subjectFemale
dc.subjectHumans
dc.subjectInfant
dc.subjectKidney
dc.subjectPyelonephritis, Xanthogranulomatous
dc.subjectTomography, X-Ray Computed
dc.subjectUltrasonography
dc.subjectabdominal radiography
dc.subjectArticle
dc.subjectbody temperature
dc.subjectbreathing rate
dc.subjectcalcium stone
dc.subjectcase report
dc.subjectchild
dc.subjectclinical article
dc.subjectclinical feature
dc.subjectcomputer assisted tomography
dc.subjectDoppler ultrasonography
dc.subjectechography
dc.subjectfemale
dc.subjecthepatomegaly
dc.subjecthistopathology
dc.subjecthuman
dc.subjecthydronephrosis
dc.subjecthyperpyrexia
dc.subjectimmune response
dc.subjectinflammation
dc.subjectkidney fibrosis
dc.subjectkidney function
dc.subjectkidney tumor
dc.subjectleukocyte count
dc.subjectlipid metabolism
dc.subjectloss of appetite
dc.subjectmacrophage
dc.subjectmale
dc.subjectnephrectomy
dc.subjectnephrolithiasis
dc.subjectphysical examination
dc.subjectplatelet count
dc.subjectrecurrent disease
dc.subjectsplenomegaly
dc.subjecttuberculin test
dc.subjecturinalysis
dc.subjecturinary tract infection
dc.subjectvomiting
dc.subjectxanthogranulomatous pyelonephritis
dc.subjectadult
dc.subjectcomplication
dc.subjectinfant
dc.subjectkidney
dc.subjectpreschool child
dc.subjectstone formation
dc.subjectx-ray computed tomography
dc.subjectxanthogranulomatous pyelonephritis
dc.titleXanthogranulomatous pyelonephritis due to calculi in a 5-year-old girl
dc.typeArticle

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