Correlation of Disease Severity and Systemic Inflammatory Markers in Patients with Chronic Rhinosinusitis with Nasal Polyps
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Date
2023
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Abstract
Objective: The aim of this study is to evaluate the relationship between Lund-Mackay scores, osteitis severity, and neutrophil lymphocyte ratio, platelet lymphocyte ratio, basophil lymphocyte ratio, eosinophil lymphocyte ratio, and systemic immune inflammation index in patients with chronic rhinosinusitis with nasal polyps. Methods: Patients who were diagnosed with chronic rhinosinusitis with nasal polyps and underwent endoscopic sinus surgery between 2014 and 2020 were evaluated retrospectively. Lund-Mackay scores and osteitis severity (Hounsfield Unit) were determined separately for each nasal cavity by examining preoperative computed tomog-raphy images. Lund-Mackay and Hounsfield Unit scores were compared with the preoperative neutrophil lympho-cyte ratio, platelet lymphocyte ratio, basophil lymphocyte ratio, eosinophil lymphocyte ratio, and systemic immune inflammation index. Results: A total of 39 patients (24 males, 15 females) (78 sides) enrolled in the study. There was a positive correlation between right-sided Lund-Mackay scores and ipsilateral Hounsfield Unit (r = 0.343, P =.033). Similarly, there was a positive correlation between left nasal cavity Lund-Mackay scores and ipsilateral Hounsfield Unit (r = 0.376; P =.018). No statistically significant correlation between Lund-Mackay scores and Hounsfield Unit values, and neutrophil lympho-cyte ratio, platelet lymphocyte ratio, basophil lymphocyte ratio, eosinophil lymphocyte ratio, and systemic immune inflammation index values were detected. Conclusion: In the present study, no correlation between chronic rhinosinusitis with nasal polyps severity and systematic inflammatory markers was demonstrated. © Author(s).