ACE genotype may have an effect on single versus multiple set preferences in strength training

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dc.contributor.authorColakoglu M.
dc.contributor.authorCam F.S.
dc.contributor.authorKayitken B.
dc.contributor.authorCetinoz F.
dc.contributor.authorColakoglu S.
dc.contributor.authorTurkmen M.
dc.contributor.authorSayin M.
dc.date.accessioned2024-07-22T08:23:48Z
dc.date.available2024-07-22T08:23:48Z
dc.date.issued2005
dc.description.abstractA polymorphic variant of the human angiotensin converting enzyme (ACE) gene was identified. The 'D' (rather than 'I') variant was associated with improvements in strength related to physical training. We set out to determine whether the response to different patterns of strength training might also differ. Ninty-nine Caucasian male non-elite athletes were randomly allocated into one of three groups: 31 non-training/ control (CG: 31), single-set (SSG: 35) and multiple-set (MSG: 33). SSG and MSG trained three times a week for 6 weeks. Both training groups were underwent a strength-training program with two mesocycles (12-15 repetition maximum (RM) and 8-12 RM mesocycles). One RM loads in half squat and bench press were assessed before training and after the first and second mesocycles. ACE polymorphisms analysed by polymerase chain reaction (PCR) methods. Subjects with ACE II genotype in the MST group had improved strength development in 12-15 RM, while SST and MST groups had similar gains in 8-12 RM. Subjects with ACE DD genotype in both the SSG and the MSG had similar benefits from both 12-15 RM and 8-12 RM. Strength gains for subjects with ACE ID genotype in the SSG were similar to MSG gains in response to 8-12 RM loads but not with 12-15 RM loads. Additionally, subjects with DD genotype had superior strength gains in both strength training groups. Tailoring strength training programmes (single-set vs. multiple set) according to the athlete's ACE genotype may be advantageous. © Springer-Verlag 2005.
dc.identifier.DOI-ID10.1007/s00421-005-1335-2
dc.identifier.issn14396319
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19686
dc.language.isoEnglish
dc.subjectAdult
dc.subjectExercise
dc.subjectExertion
dc.subjectGenotype
dc.subjectHumans
dc.subjectMale
dc.subjectPeptidyl-Dipeptidase A
dc.subjectPhysical Education and Training
dc.subjectPhysical Fitness
dc.subjectWeight Lifting
dc.subjectdipeptidyl carboxypeptidase
dc.subjectadult
dc.subjectarticle
dc.subjectathlete
dc.subjectCaucasian
dc.subjectcontrolled study
dc.subjectenzyme activity
dc.subjectenzyme polymorphism
dc.subjectexercise
dc.subjectgenetic analysis
dc.subjectgenetic variability
dc.subjectgenotype
dc.subjecthuman
dc.subjecthuman experiment
dc.subjectmale
dc.subjectmuscle strength
dc.subjectnormal human
dc.subjectpolymerase chain reaction
dc.subjectpriority journal
dc.subjectrandomization
dc.titleACE genotype may have an effect on single versus multiple set preferences in strength training
dc.typeArticle

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