Comparison of Three Different Administration Positions for Intratracheal Beractant in Preterm Newborns with Respiratory Distress Syndrome

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dc.contributor.authorKaradag A.
dc.contributor.authorOzdemir R.
dc.contributor.authorDegirmencioglu H.
dc.contributor.authorUras N.
dc.contributor.authorDilmen U.
dc.contributor.authorBilgili G.
dc.contributor.authorErdeve O.
dc.contributor.authorCakir U.
dc.contributor.authorAtasay B.
dc.date.accessioned2024-07-22T08:12:07Z
dc.date.available2024-07-22T08:12:07Z
dc.date.issued2016
dc.description.abstractBackground The aim of this study was to compare the efficacy and adverse effects of various intratracheal beractant administration positions in preterm newborns with respiratory distress syndrome. Methods This study was performed on preterm newborns with respiratory distress syndrome. The inclusion criteria were being between 26 weeks and 32 weeks of gestational age, having a birth weight between 600 g and 1500 g, having received clinical and radiological confirmation for the diagnosis of respiratory distress syndrome (RDS) within 3 hours of life, having been born in one of the centers where the study was carried out, and having fractions of inspired oxygen (FiO2) ≥ 0.40 to maintain oxygen saturation by pulse oximeter at 88-96%. Beractant was administered in four positions to Group I newborns, in two positions to Group II, and in neutral position to Group III. Results Groups I and II consisted of 42 preterm infants in each whereas Group III included 41 preterm infants. No significant differences were detected among the groups with regards to maternal and neonatal risk factors. Groups were also similar in terms of the following complications: patent ductus arteriosus (PDA), pneumothorax, intraventricular hemorrhage (IVH), chronic lung disease (CLD), retinopathy of prematurity (ROP), necrotising enterocolitis (NEC), death within the first 3 days of life, death within the first 28 days of life, and rehospitalization within 1 month after discharge. Neither any statistically significant differences among the parameters related with surfactant administration, nor any significant statistical differences among the FiO2 levels and the saturation levels before and after the first surfactant administration among the groups were determined. Conclusion In terms of efficacy and side effects, no important difference was observed between the recommended four position beractant application, the two position administration, and the neutral position. Copyright © 2016, Taiwan Pediatric Association.
dc.identifier.DOI-ID10.1016/j.pedneo.2015.04.012
dc.identifier.issn18759572
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/15921
dc.language.isoEnglish
dc.publisherElsevier (Singapore) Pte Ltd
dc.rightsAll Open Access; Gold Open Access
dc.subjectBiological Products
dc.subjectFemale
dc.subjectHumans
dc.subjectInfant, Newborn
dc.subjectInfant, Premature
dc.subjectIntubation, Intratracheal
dc.subjectMale
dc.subjectPatient Positioning
dc.subjectPulmonary Surfactants
dc.subjectRespiratory Distress Syndrome, Newborn
dc.subjectberactant
dc.subjectsteroid
dc.subjectberactant
dc.subjectbiological product
dc.subjectlung surfactant
dc.subjectArticle
dc.subjectbirth weight
dc.subjectbody position
dc.subjectbrain hemorrhage
dc.subjectchronic lung disease
dc.subjectcomparative study
dc.subjectcontrolled study
dc.subjectdrug efficacy
dc.subjectdrug safety
dc.subjectendotracheal tube
dc.subjectextubation
dc.subjectfemale
dc.subjectgestational age
dc.subjecthead position
dc.subjecthospital readmission
dc.subjecthuman
dc.subjectlung hemorrhage
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmulticenter study
dc.subjectnecrotizing enterocolitis
dc.subjectneonatal respiratory distress syndrome
dc.subjectnewborn
dc.subjectnewborn mortality
dc.subjectoxygen saturation
dc.subjectpatent ductus arteriosus
dc.subjectpatient positioning
dc.subjectpneumothorax
dc.subjectprematurity
dc.subjectpulse oximeter
dc.subjectpulse oximetry
dc.subjectrandomized controlled trial
dc.subjectretrolental fibroplasia
dc.subjectrisk factor
dc.subjectsepsis
dc.subjectsupine position
dc.subjectthorax radiography
dc.subjectclinical trial
dc.subjectendotracheal intubation
dc.subjectprematurity
dc.subjectRespiratory Distress Syndrome, Newborn
dc.titleComparison of Three Different Administration Positions for Intratracheal Beractant in Preterm Newborns with Respiratory Distress Syndrome
dc.typeArticle

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