Serum her-2/neu and survivin levels and their relationship to histological parameters in early-stage breast cancer

dc.contributor.authorGoksel, G
dc.contributor.authorTaneli, F
dc.contributor.authorUslu, R
dc.contributor.authorUlman, C
dc.contributor.authorDinc, G
dc.contributor.authorCoskun, T
dc.contributor.authorKandiloglu, AR
dc.date.accessioned2025-04-10T10:34:40Z
dc.date.available2025-04-10T10:34:40Z
dc.description.abstractThis study was conducted to investigate the serum levels of her-2/neu and survivin in patients with early-stage breast cancer and their relationship with known histological parameters. Forty-one patients with early-stage breast cancer were investigated. Serum samples were collected from patients on their first admission before adjuvant chemotherapy, and from healthy controls. Serum her-2/neu and survivin levels were determined using an enzyme-linked immunosorbent assay. There was no difference in the levels of serum her-2/neu and survivin between the breast cancer patients and the control group. Serum her-2/neu concentration showed moderate correlations with disease stage and the Ki-67 level, and the serum survivin level showed a moderate correlation with progesterone receptor concentration. Serum levels of her-2/neu and survivin were not significantly related to age and histological parameters in patients with early-stage breast cancer. However, much research continues on the prognostic value of serum her-2/neu and survivin levels, and important new knowledge may ultimately emerge.
dc.identifier.issn0300-0605
dc.identifier.urihttp://hdl.handle.net/20.500.14701/40798
dc.language.isoEnglish
dc.titleSerum her-2/neu and survivin levels and their relationship to histological parameters in early-stage breast cancer
dc.typeArticle

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