Two challenging cases of pituicytoma

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dc.contributor.authorOzisik H.
dc.contributor.authorYurekli B.S.
dc.contributor.authorSimsir I.Y.
dc.contributor.authorErtan Y.
dc.contributor.authorEraslan C.
dc.contributor.authorOzdemir N.
dc.contributor.authorOzgiray E.
dc.contributor.authorSaygili F.
dc.date.accessioned2024-07-22T08:05:22Z
dc.date.available2024-07-22T08:05:22Z
dc.date.issued2021
dc.description.abstractIntroduction: Pituicytoma is a rare tumor of the pituitary gland derived from neurohypophyseal pituicytes. Case 1: A 58-year-old female presented with decreased vision; she was admitted to the neurosurgery department of Ege University after the detection of a pituitary macroadenoma. Magnetic resonance imaging (MRI) showed a 28 * 18 * 17-mm suprasellar mass, and laboratory tests revealed hypopituitarism. Hydrocortisone and L-thyroxine treatment were initiated, and the patient underwent resection through the endoscopic endonasal approach (EEA). The histopathological examination revealed a pituicytoma. The recurrence of tumor was detected during the 1-year follow-up, and the patient is awaiting surgery. Case 2: A 70-year-old woman presented with visual changes; she had a past medical history of hypophyseal macroadenoma and pituicytoma resected through an EEA in 2012 and 2017, respectively. During follow-up, 2 years after the second surgery, MRI showed progression of the pituicytoma then measuring 38 × 23 × 22 mm; it had invaded the cavernous sinus and was causing hydrocephaly and panhypopituitarism. The patient underwent the third resection through the transcranial approach in order to minimize bleeding. After this surgery, the patient developed diabetes insipidus and underwent treatment with desmopressin. Histopathological examination revealed a pituicytoma. At 6-month follow-up, imaging showed a sellar suprasellar mass 37 × 22 × 24 mm invading the cavernous sinus, indicative of recurrence. In the postoperative period, the patient applied to the department of radiation oncology to have fractionated radiotherapy. Discussion: Pituicytomas are known to be low-grade tumors; because of their rarity, they are a real challenge. These patients should be followed up closely. © 2021, Hellenic Endocrine Society.
dc.identifier.DOI-ID10.1007/s42000-021-00301-6
dc.identifier.issn11093099
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13104
dc.language.isoEnglish
dc.publisherSpringer Science and Business Media Deutschland GmbH
dc.subjectAged
dc.subjectFemale
dc.subjectGlioma
dc.subjectHumans
dc.subjectMagnetic Resonance Imaging
dc.subjectMiddle Aged
dc.subjectPituitary Gland
dc.subjectPituitary Neoplasms
dc.subjectdesmopressin
dc.subjectfollitropin
dc.subjectglial fibrillary acidic protein
dc.subjecthomeobox protein Nkx 2.1
dc.subjecthydrocortisone
dc.subjectKi 67 antigen
dc.subjectlevothyroxine
dc.subjectluteinizing hormone
dc.subjectsomatomedin C
dc.subjectthyrotropin
dc.subjectthyroxine
dc.subjectadult
dc.subjectaged
dc.subjectangiography
dc.subjectcase report
dc.subjectcavernous sinus
dc.subjectclinical article
dc.subjectdiabetes insipidus
dc.subjectdisease exacerbation
dc.subjectendoscopic endonasal surgery
dc.subjectfemale
dc.subjectfollow up
dc.subjectfree thyroxine index
dc.subjecthistopathology
dc.subjecthuman
dc.subjecthuman cell
dc.subjecthuman tissue
dc.subjecthydrocephalus
dc.subjecthypophysis tumor
dc.subjecthypopituitarism
dc.subjectimmunohistochemistry
dc.subjectinterventional radiology
dc.subjectlaboratory test
dc.subjectmacroadenoma
dc.subjectmedical history
dc.subjectmiddle aged
dc.subjectnuclear magnetic resonance imaging
dc.subjectoptic chiasm
dc.subjectpituicytoma
dc.subjectpostoperative period
dc.subjectpreoperative period
dc.subjectproliferation index
dc.subjectradioembolization
dc.subjectReview
dc.subjectspindle cell
dc.subjecttumor invasion
dc.subjecttumor recurrence
dc.subjecttumor volume
dc.subjectTurkey (republic)
dc.subjectvisual impairment
dc.subjectdiagnostic imaging
dc.subjectglioma
dc.subjecthypophysis
dc.subjecthypophysis tumor
dc.subjectphysiology
dc.titleTwo challenging cases of pituicytoma
dc.typeReview

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