Antimicrobial activity of the essential oil of Thymus capitatus against Helicobacter pylori

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dc.contributor.authorGüvenir M.
dc.contributor.authorHanoğlu D.
dc.contributor.authorHano-Lu A.
dc.contributor.authorSüer K.
dc.contributor.authorBaşer H.C.
dc.contributor.authorYavuz D.Ö.
dc.contributor.authorŞalidağ T.
dc.date.accessioned2024-07-22T08:08:00Z
dc.date.available2024-07-22T08:08:00Z
dc.date.issued2020
dc.description.abstractHelicobacter pylori (H.pylori) is an infective agent and the main resourceful factor of chronic, active type B gastritis, peptic and duodenal ulcer, gastric carcinoma and mucosa-associated lymphoid tumors. Nowadays, pharmcological treatment of H. pylori infections attracts attention besides antibiotic treatment. The aim of this study is to analyse the chemical composition of the essential oils of Thymus capitatus and the antimicrobial activity against H. pylori. Aerial parts of wild-growing plant materials were collected during the flowering stage from three different locations. Essential oil composition analyses were performed simultaneously by GC-FID and GC-MS systems. The antimicrobial activity of the essential oil was tested by broth dilution method. The thymol percentage was determined as more than half of the essential oil composition of Thymus capitatus-Yedidalga (51.9%) and Thymus capitatus ñYıldırım (57.1%); however, the composition of thymol was 47.2% followed by 15.1% (p-cymene), 10.0% (γ-terpinene) and 5.7% (carvacrol) for Thymus capitatus-Boğaz/Girne. The essential oil from Thymus capitatus- Boğaz/Girne showed the lowest MIC and MBC values and the strongest bactericidal activity against H. pylori compared to the other tested essential oils. Bactericidal efficacy of essential oil of Thymus capitatus on H. pylori could have been affected due to the varied rates of major compounds. Thymus capitatus essential oil could be an alternative way for the treatment of H. pylori infections. © 2020 by Polish Pharmaceutical Society.
dc.identifier.DOI-ID10.32383/appdr/115518
dc.identifier.issn00016837
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/14201
dc.language.isoEnglish
dc.publisherPolish Pharmaceutical Society
dc.rightsAll Open Access; Bronze Open Access
dc.subject1 octen 3 ol
dc.subject4 cymen 8 ol
dc.subjectalpha bisabolene
dc.subjectalpha thujene
dc.subjectantibiotic agent
dc.subjectborneol
dc.subjectcamphene
dc.subjectcarvacrol
dc.subjectcarvone
dc.subjectcaryophyllene oxide
dc.subjectcitral
dc.subjectclarithromycin
dc.subjectessential oil
dc.subjecteugenol
dc.subjectgeraniol
dc.subjectisocarvacrol
dc.subjectledene
dc.subjectlimonene
dc.subjectlinalool
dc.subjectmyrcene
dc.subjectnerol
dc.subjectpara cymene
dc.subjectpinene
dc.subjectsabinene
dc.subjectspathulenol
dc.subjectterpinene
dc.subjectterpineol
dc.subjectterpinolene
dc.subjectthymol
dc.subjectThymus capitatus essential oil
dc.subjectunclassified drug
dc.subjectArticle
dc.subjectbactericidal activity
dc.subjectbroth dilution
dc.subjectchemical composition
dc.subjectcontrolled study
dc.subjectdrug efficacy
dc.subjectflowering
dc.subjectHelicobacter pylori
dc.subjectmass fragmentography
dc.subjectminimum bactericidal concentration
dc.subjectminimum inhibitory concentration
dc.subjectnonhuman
dc.subjectthymus
dc.subjectThymus capitatus
dc.titleAntimicrobial activity of the essential oil of Thymus capitatus against Helicobacter pylori
dc.typeArticle

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