Detection of endothelial dysfunction in preeclamptic patients by using color Doppler sonography

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dc.contributor.authorKuscu N.K.
dc.contributor.authorKurhan Z.
dc.contributor.authorYildirim Y.
dc.contributor.authorTavli T.
dc.contributor.authorKoyuncu F.
dc.date.accessioned2024-07-22T08:25:01Z
dc.date.available2024-07-22T08:25:01Z
dc.date.issued2003
dc.description.abstractOur goal in this study was to detect endothelial function in normal and preeclamptic patients by using color Doppler sonography and plasma fibronectin levels. The increased ratio of the brachial artery diameter during shear stress, and plasma fibronectin levels were measured in 15 preeclamptic and 11 normal, gestational-age matched pregnant patients. The test was repeated at the postpartum second and sixth weeks in the preeclamptic group. In addition, the plasma fibronectin levels of all patients were measured. The increased ratios were 4.26±0.69% vs 12.18±1.97% in the preeclamptic and normal patients, respectively (P=0.003). At the second and sixth postpartum weeks, the ratios were 6.67±0.89% and 9.27±1.16% in the preeclamptic group, revealing a significant improvement in the sixth week (P=0.001). Fibronectin levels were 0.80±0.11 g/L vs 0.45±0.06 g/L in preeclamptic and normal patients (P=0.01). The correlation coefficient between the fibronectin levels and increase rate was r=-0.38 and P=0.05. We conclude that endothelial dysfunction, which is fundamental to preeclampsia, can be detected by using color Doppler sonography.
dc.identifier.DOI-ID10.1007/s00404-002-0351-2
dc.identifier.issn09320067
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20234
dc.language.isoEnglish
dc.publisherSpringer Verlag
dc.subjectfibronectin
dc.subjectadult
dc.subjectartery diameter
dc.subjectartery dilatation
dc.subjectarticle
dc.subjectbrachial artery
dc.subjectclinical article
dc.subjectcolor ultrasound flowmetry
dc.subjectcontrolled study
dc.subjectdiastolic blood pressure
dc.subjectendothelium injury
dc.subjectfemale
dc.subjectgestational age
dc.subjecthuman
dc.subjectpreeclampsia
dc.subjectprotein determination
dc.subjectpuerperium
dc.subjectshear stress
dc.subjectsystolic blood pressure
dc.titleDetection of endothelial dysfunction in preeclamptic patients by using color Doppler sonography
dc.typeArticle

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