An important source of preanalytical error in medical laboratories: Centrifugation

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dc.contributor.authorSonmez C.
dc.contributor.authorGümüs A.
dc.contributor.authorSenes M.
dc.contributor.authorAykal G.
dc.contributor.authorTaneli F.
dc.contributor.authorAksungar F.
dc.contributor.authorAvci E.
dc.contributor.authorCoskun C.
dc.contributor.authorÇinaroglu I.
dc.contributor.authorColak A.
dc.contributor.authorEker P.
dc.contributor.authorGüçel F.
dc.contributor.authorHakligor A.
dc.contributor.authorInal B.B.
dc.contributor.authorOrhan B.
dc.contributor.authorYilmaz C.
dc.date.accessioned2024-07-22T08:05:42Z
dc.date.available2024-07-22T08:05:42Z
dc.date.issued2021
dc.description.abstractCentrifugation separates particles within the specimen according to their shape, dimensions, and density and basically can be defined as a separation method. The centrifuge is an essential device in medical laboratories to prepare the serum, plasma, and urine samples for analysis. It is basically an electric device composed of the stationary (motor) and the motile (rotor) part. The centrifugation depends on two main variables: relative centrifugal force (RCF) and centrifugation time. The physical impact separating the specimen into its components in the centrifuge known as RCF is expressed as the multiples of gravitational acceleration (×g). RPM, defined as the number of rotations of the centrifuge perminute, shows the speed of the centrifuge. RCF value can be calculated by using RPM, and the centrifuge radius. Because models and sizes of centrifuges vary considerably, the use of gravity (g) forces instead of RPM is suggested. The centrifuges can be classified according to their usage, speed, technical specifications, and rotor type. An accurate and precise centrifugation process is essential to prevent errors in the preanalytical phase. The purpose of this document is to ensure the standardization of a good, precise protocol for the centrifugation process among the medical laboratories. © 2021 De Gruyter. All rights reserved.
dc.identifier.DOI-ID10.1515/TJB-2020-0262
dc.identifier.issn02504685
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13232
dc.language.isoEnglish
dc.publisherDe Gruyter Open Ltd
dc.rightsAll Open Access; Gold Open Access
dc.subjectacceleration
dc.subjectanalytical error
dc.subjectanticoagulation
dc.subjectArticle
dc.subjectautomation
dc.subjectblood clot
dc.subjectblood clotting disorder
dc.subjectblood clotting time
dc.subjectcentrifugal force
dc.subjectcentrifugation
dc.subjectgravity
dc.subjecthuman
dc.subjectlipid analysis
dc.subjectphysical activity
dc.subjectplatelet count
dc.subjectpre-analytical phase
dc.subjectprotein purification
dc.subjectRNA isolation
dc.subjecttemperature measurement
dc.subjectthrombocyte rich plasma
dc.subjectultracentrifugation
dc.subjecturine sampling
dc.titleAn important source of preanalytical error in medical laboratories: Centrifugation
dc.typeArticle

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