Acoustic actuation of in situ fabricated artificial cilia

dc.contributor.authorOrbay S.
dc.contributor.authorOzcelik A.
dc.contributor.authorBachman H.
dc.contributor.authorHuang T.J.
dc.date.accessioned2024-07-22T08:09:56Z
dc.date.available2024-07-22T08:09:56Z
dc.date.issued2018
dc.description.abstractWe present on-chip acoustic actuation of in situ fabricated artificial cilia. Arrays of cilia structures are UV polymerized inside a microfluidic channel using a photocurable polyethylene glycol (PEG) polymer solution and photomasks. During polymerization, cilia structures are attached to a silane treated glass surface inside the microchannel. Then, the cilia structures are actuated using acoustic vibrations at 4.6 kHz generated by piezo transducers. As a demonstration of a practical application, DI water and fluorescein dye solutions are mixed inside a microfluidic channel. Using pulses of acoustic excitations, and locally fabricated cilia structures within a certain region of the microchannel, a waveform of mixing behavior is obtained. This result illustrates one potential application wherein researchers can achieve spatiotemporal control of biological microenvironments in cell stimulation studies. These acoustically actuated, in situ fabricated, cilia structures can be used in many on-chip applications in biological, chemical and engineering studies. © 2018 IOP Publishing Ltd.
dc.identifier.DOI-ID10.1088/1361-6439/aaa0ae
dc.identifier.issn09601317
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/15009
dc.language.isoEnglish
dc.publisherInstitute of Physics Publishing
dc.rightsAll Open Access; Green Open Access
dc.subjectAcoustic transducers
dc.subjectDyes
dc.subjectFluidic devices
dc.subjectMicrochannels
dc.subjectMicrofluidics
dc.subjectAcoustic actuations
dc.subjectacoustofluidics
dc.subjectArtificial cilia
dc.subjectBiological microenvironments
dc.subjectMicro-mixing
dc.subjectMicrofluidic channel
dc.subjectOn-chip applications
dc.subjectSpatiotemporal control
dc.subjectFabrication
dc.titleAcoustic actuation of in situ fabricated artificial cilia
dc.typeArticle

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