The effect of cigarette smoking during pregnancy on cord blood lipid, lipoprotein and apolipoprotein levels

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dc.contributor.authorIşcan A.
dc.contributor.authorYiǧitoǧlu M.R.
dc.contributor.authorEce A.
dc.contributor.authorAri Z.
dc.contributor.authorAkyildiz M.
dc.date.accessioned2024-07-22T08:25:59Z
dc.date.available2024-07-22T08:25:59Z
dc.date.issued1997
dc.description.abstractWe examined the relationship between maternal smoking during pregnancy and serum lipid, lipoprotein and apolipoprotein levels in newborns. Serum concentrations of total cholesterol, triglyceride, high density lipoprotein cholesterol, low density lipoprotein cholesterol, apolipoprotein A-1, apolipoprotein B and lipoprotein (a) were assesed in blood samples from 38 mothers who were smokers and their newborns obtained at delivery and compared to blood sample from 42 nonsmokers and their newborns. As compared with newborns of nonsmoker mothers, newborns of smoker mothers showed a lower mean level of high density lipoprotein cholesterol (21 versus 26 mg/dl, p < 0.01), a higher total cholesterol to high density lipoprotein cholesterol (4.7 versus 3.7, P < 0.01), a higher low density lipoprotein cholesterol to high density lipoprotein cholesterol ratios (3.2 versus 2.3, p < 0.05), a lower mean level of apolipoprotein A-1 (105 versus 129 mg/dl, p < 0.01) and a higher apolipoprotein B to apolipoprotein A-1 ratio (0.44 versus 0.3, p < 0.01). These paremeters were also different between smoker and nonsmoker mothers. There were no significant differences in TC, TG, LDL-C, Apo B and Lp (a) values between the two newborn groups. These data suggest that maternal smoking during pregnancy markedly affects lipid metabolism in the fetus.
dc.identifier.DOI-ID10.1536/ihj.38.497
dc.identifier.issn00214868
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20675
dc.language.isoEnglish
dc.publisherInternational Heart Journal Association
dc.rightsAll Open Access; Bronze Open Access
dc.subjectapolipoprotein
dc.subjectapolipoprotein A1
dc.subjectapolipoprotein B
dc.subjectcholesterol
dc.subjecthigh density lipoprotein cholesterol
dc.subjectlipid
dc.subjectlipoprotein
dc.subjectlipoprotein A
dc.subjectlow density lipoprotein cholesterol
dc.subjecttriacylglycerol
dc.subjectadult
dc.subjectarticle
dc.subjectcholesterol blood level
dc.subjectcigarette smoking
dc.subjectcontrolled study
dc.subjectfemale
dc.subjecthuman
dc.subjecthuman experiment
dc.subjectlipid blood level
dc.subjectlipid metabolism
dc.subjectlipoprotein blood level
dc.subjectmale
dc.subjectnewborn
dc.subjectnormal human
dc.subjectpregnancy
dc.subjectpriority journal
dc.subjecttriacylglycerol blood level
dc.subjectumbilical cord blood
dc.titleThe effect of cigarette smoking during pregnancy on cord blood lipid, lipoprotein and apolipoprotein levels
dc.typeArticle

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