Plasma selenium levels in celiac disease patients on a gluten -free diet; [Glutensiz diyet alan çölyak hastası çocuklarda serum selenyum düzeyleri]
| dc.contributor.author | Ünal F. | |
| dc.contributor.author | Umman C. | |
| dc.contributor.author | Tok A.C. | |
| dc.contributor.author | Semizel E. | |
| dc.contributor.author | Ecevit C.O. | |
| dc.contributor.author | Özdemir S. | |
| dc.contributor.author | Taneli F. | |
| dc.contributor.author | Kasirga E. | |
| dc.date.accessioned | 2024-07-22T08:19:48Z | |
| dc.date.available | 2024-07-22T08:19:48Z | |
| dc.date.issued | 2012 | |
| dc.description.abstract | Introduction: Celiac disease (CD) is a gluten-induced enteropathy that results in malabsorption of nutrients such as selenium. A high incidence of malignancy in CD has been previously reported. Selenium is known to have a protective role against cancer. This study aimed to investigate whether there is an effect on serum selenium levels in children with CD on a gluten-free diet. Materials and Methods: Serum levels of selenium were studied in 17 children (mean age 5.64±3.30 years) with CD and 20 age-and gender-matched healthy children. CD was diagnosed according to ESPGHAN criteria. All the patients were clinically well and had been on gluten-free diets for 11.11±1.98 (mean±SE) months. All patients were fully consistent with the diet. The concentration of selenium was determined by a periodically validated atomic absorption spectrometer (Perkin Elmer AAS 700 system). Wet ashing procedure was used for all samples and controls. Results: In CD group one child's (5.8%), and in control group three children's (%15) serum selenium levels were found under normal limits. There was no statistically significant difference between serum selenium levels and the duration of gluten free diet (p>0.05). There was no statistically significant difference in serum selenium levels between celiac patients (124.19±12.31 μg/L) and control group (92.47±12.06 μg/L), (p>0.05). Discussion: It can be concluded that, normal levels of serum selenium in children with CD can be achieved with fully compatible gluten-free diet and a balanced diet which supplies daily selenium requirement. © The Journal of Current Pediatrics, published by Galenos Publishing. | |
| dc.identifier.issn | 13049054 | |
| dc.identifier.uri | http://akademikarsiv.cbu.edu.tr:4000/handle/123456789/17855 | |
| dc.language.iso | English | |
| dc.publisher | Galenos Yayincilik, | |
| dc.subject | selenium | |
| dc.subject | article | |
| dc.subject | atomic absorption spectrometry | |
| dc.subject | celiac disease | |
| dc.subject | child | |
| dc.subject | clinical article | |
| dc.subject | controlled study | |
| dc.subject | gluten free diet | |
| dc.subject | human | |
| dc.subject | outcome assessment | |
| dc.subject | preschool child | |
| dc.subject | treatment duration | |
| dc.title | Plasma selenium levels in celiac disease patients on a gluten -free diet; [Glutensiz diyet alan çölyak hastası çocuklarda serum selenyum düzeyleri] | |
| dc.type | Article |